SCHEMBL3039623

SCHEMBL3039623

O=S(=O)(c1ccc(Cl)cc1-c1ccccc1)c1ccc(Cl)cc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.46
ACLY P53396 1/20 0.46
KIF18A Q8NI77 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
KDM4E B2RXH2 1/20 0.42
PGR P06401 1/20 0.41
CYP1A2 P05177 1/20 0.41
HSD11B1 P28845 1/20 0.41
OPRK1 P41145 2/20 0.41
CNR1 P21554 1/20 0.41
NTSR1 P30989 1/20 0.41
PDE4D Q08499 1/20 0.41
FBP1 P09467 1/20 0.41
PTGS2 P35354 2/20 0.41
PTGS1 P23219 1/20 0.41
ITGA1 P56199 2/20 0.40
ALB P02768 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2019763 0.90 KIF18A (0.55) KIF18AKMT2AKDM4EPTGS2PTGS1
SCHEMBL10977080 0.88 S100A4 (0.45) S100A4KIF18AKMT2AMEN1PTGS2
SCHEMBL3446869 0.87 PGR (0.43) S100A4KMT2AMEN1PGRNAT1
SCHEMBL7584026 0.85 PTGS2 (0.50) S100A4ACLYPTGDR2KMT2AMEN1
SCHEMBL8178017 0.85 PTGDR2 (0.46) S100A4ACLYKIF18APTGDR2KMT2A
SCHEMBL29233503 0.82 ACLY (0.42) S100A4ACLYKIF18APTGDR2KMT2A
SCHEMBL11340874 0.81 POLB (0.44) S100A4KMT2AMEN1FBP1
SCHEMBL3671582 0.81 PTGS2 (0.46) S100A4KDM4EPTGS2PTGS1GABRP
SCHEMBL3446890 0.79 PTPN1 (0.50) S100A4KIF18AKMT2AKDM4EITGA1
SCHEMBL11572510 0.79 TDP1 (0.57) S100A4ACLYPTGDR2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3558250-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'Oréal (FR) 2019-10-30 EP claimed
WO-2018115273-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'OREAL (FR) 2018-06-28 WO claimed
US-9580615-B2 Phase change inks comprising inorganic nucleating agents XEROX CORPORATION (US) 2017-02-28 US claimed
US-8814999-B2 Phase change ink compositions comprising crystalline sulfone compounds and derivatives thereof XEROX CORPORATION (US) 2014-08-26 US claimed
US-20130284062-A1 PHASE CHANGE INK COMPOSITIONS COMPRISING CRYSTALLINE SULFONE COMPOUNDS AND DERIVATIVES THEREOF XEROX CORPORATION (US) 2013-10-31 US claimed
US-20200031796-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'OREAL (FR) 2020-01-30 US disclosed
EP-3558250-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'Oréal (FR) 2019-10-30 EP disclosed
US-10292920-B2 Composition for dyeing keratin fibers L'OREAL (FR) 2019-05-21 US disclosed
US-20180353412-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS L'OREAL (FR) 2018-12-13 US disclosed
EP-3386470-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2018-10-17 EP disclosed
EP-3383499-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2018-10-10 EP disclosed
EP-3164108-B1 COMPOSITION FOR DYEING KERATIN FIBERS OREAL (FR) 2018-10-03 EP disclosed
WO-2002072519-A2 PROCESS CATALYSED BY FLUOROALKYLSULFONATED COMPOUNDS, PREFERABLY BIS-TRIFLIMIDE COMPOUNDS THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2002-09-19 WO disclosed
US-4058604-A OR ACARICIDALLY ACTIVE SUBSTANCES CIBA-GEIGY AG (CH) 1977-11-15 US disclosed
US-4018926-A Alkyl 4-[o-(substituted methyleneamino)-phenyl]-3-thioallophanate miticides and fungicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-19 US disclosed
US-4011213-A FUNGICIDES, MITE OVICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-03-08 US disclosed
US-3980799-A OR ACARICIDALLY ACTIVE SUBSTANCES CIBA-GEIGY AG (CH) 1976-09-14 US disclosed
US-3958007-A FUNGICIDES, MITE OVICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-18 US disclosed
US-3950391-A FUNGICIDES, MITICIDES, OVICIDES ADAMS CHARLES D 1976-04-13 US disclosed
US-3940412-A 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them CIBA-GEIGY AG (CH) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180353412-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, CUTA, DSG1 S100A4 19/4885ACLY 1861/4885KIF18A 283/4885
US-10292920-B2 Composition for dyeing keratin fibers KRT18, IK, S100A10 S100A4 12/4885ACLY 3802/4885KIF18A 549/4885
US-20200031796-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION KRT18, KRTCAP2, MUC1 S100A4 15/4885ACLY 4606/4885KIF18A 1019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.