Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247809 | 0.84 | KDM4E (0.38) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL6005339 | 0.72 | TRPM8 (0.46) | KMT2AMEN1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL28449626 | 0.70 | L3MBTL1 (0.42) | KMT2AMEN1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL25396869 | 0.70 | NOTUM (0.38) | GAAMAPTHTTCYP3A4TSHR | |
| SCHEMBL20564934 | 0.70 | KMT2A (0.36) | KDM4EKMT2AMAPTMEN1HTT | |
| SCHEMBL17102731 | 0.70 | SMN1; SMN2 (0.39) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL650663 | 0.70 | MAPT (0.45) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL16968516 | 0.69 | TACR1 (0.47) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3342286 | 0.69 | KMT2A (0.35) | KMT2AGAAMAPTMEN1HTT | |
| SCHEMBL17220649 | 0.69 | ALDH1A1 (0.40) | KDM4EKMT2AGAAMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617772-B1 | POLYPHENYLENE ETHER RESIN COMPOSITION AND MOLDED ARTICLE OF SAME | MITSUBISHI ENG PLASTICS CORP (JP) | 2020-02-12 | — | — | EP | disclosed |
| EP-2617772-A1 | POLYPHENYLENE ETHER RESIN COMPOSITION AND MOLDED ARTICLE OF SAME | Mitsubishi Engineering-Plastics Corporation (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-7763610-B2 | Carboxylic acid derived benzoxazines as agents for the treatment of respiratory diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20100160501-A1 | FLAME-RETARDANT POLYAMIDE RESIN COMPOSITION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20060194797-A1 | Condensed ring compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194797-A1 | Condensed ring compound and use thereof | CYSLTR2, CYSLTR1, LTB4R2 | MMP2 3597/4885KDM4E 4168/4885TTR 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.