SCHEMBL367217

SCHEMBL367217

C=CCOS(=O)(=O)CCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
FAAH O00519 2/20 0.42
PRKCA P17252 1/20 0.39
CA2 P00918 9/20 0.38
CA1 P00915 8/20 0.38
CA9 Q16790 7/20 0.38
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
SMPD1 P17405 2/20 0.38
GLA P06280 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
EPHX2 P34913 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30894 0.98 TSHR (0.42) TSHRFAAHPRKCACA2CA1
SCHEMBL27697007 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
Ammonia Solution, Strong SCHEMBL1646993 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
SCHEMBL28215322 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
SCHEMBL564197 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
Formaldehyde SCHEMBL5810344 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
SCHEMBL3275569 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
SCHEMBL1149979 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
Hydrochloric Acid SCHEMBL11668127 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1
Methane SCHEMBL27691198 0.96 TSHR (0.41) TSHRFAAHPRKCACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112545911-A Compositions, care agents, uses and methods for reducing skin irritation 华熙生物科技股份有限公司 2021-03-26 CN claimed
CN-102504078-A Method for preparing electrolyte-resisting thickening agent ZHEJIANG JINGYE BIOCHEMICAL CO LTD 2012-06-20 CN claimed
US-20240238303-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF ENALARE THERAPEUTICS INC (US) 2024-07-18 US disclosed
EP-4398863-A1 THERMO-SENSITIVE COMPOSITION AND METHOD FOR PREPARATION THEREOF BASF SE (DE) 2024-07-17 EP disclosed
US-20240226007-A1 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) COMPOSITIONS, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Sovida Solutions Ltd. (GB) 2024-07-11 US disclosed
US-12016939-B2 Skin treatment methods and compositions for transdermal delivery of active agents TOPIX PHARMACEUTICALS, INC. (US) 2024-06-25 US disclosed
US-20240108556-A1 SCAR TREATMENT COMPOSITION TOPIX PHARMACEUTICALS, INC. 2024-04-04 US disclosed
US-20240091122-A1 Growth Factor Formulation TOPIX PHARMACEUTICALS, INC. 2024-03-21 US disclosed
EP-4333852-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Enalare Therapeutics Inc. (US) 2024-03-13 EP disclosed
EP-4333807-A1 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) COMPOSITIONS, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Sovida Solutions Ltd. (GB) 2024-03-13 EP disclosed
US-20240075112-A1 SCAR TREATMENT COMPOSITION TOPIX PHARMACEUTICALS, INC. 2024-03-07 US disclosed
US-4797223-A ANIONIC, CATIONIC OR NONIONIC SURFACTANTS ROHM AND HAAS COMPANY (US) 1989-01-10 US disclosed
US-4647309-A Waterborne firm coating for temporary protection of parts, providing controlled lubrication during assembly ASHLAND OIL, INC. (US) 1987-03-03 US disclosed
US-4612054-A Carbodiimide driers for resin coating compositions ASHLAND OIL, INC. (US) 1986-09-16 US disclosed
US-4479981-A CORROSION RESISTANCE ASHLAND OIL, INC. (US) 1984-10-30 US disclosed
US-4444803-A Water-borne soft coating compositions and processes therefor ASHLAND OIL, INC. (US) 1984-04-24 US disclosed
US-4444802-A WAXES, ESTERS, ALCOHOLIC COUPLING SOLVENT ASHLAND OIL, INC. (US) 1984-04-24 US disclosed
EP-0093324-A1 Water-borne firm coating compositions and processes therefor ASHLAND OIL, INC. (US) 1983-11-09 EP disclosed
EP-0093323-A1 Water-borne hard coating compositions and processes therefor ASHLAND OIL, INC. (US) 1983-11-09 EP disclosed
EP-0093388-A2 Water-borne soft coating compositions and processes therefor ASHLAND OIL, INC. (US) 1983-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108556-A1 SCAR TREATMENT COMPOSITION MMP1, MMP8, PLAT TSHR 4627/4885FAAH 374/4885PRKCA 3318/4885
US-20240075112-A1 SCAR TREATMENT COMPOSITION MMP1, MMP8, MMP2 TSHR 4116/4885FAAH 561/4885PRKCA 3143/4885
US-20240238303-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF KCNN2, KCNN1, KCNN3 TSHR 3264/4885FAAH 3789/4885PRKCA 393/4885
US-12016939-B2 Skin treatment methods and compositions for transdermal delivery of active agents CUTA, MMP1, TYR TSHR 1984/4885FAAH 502/4885PRKCA 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.