SCHEMBL3672180

SCHEMBL3672180

Cc1c(N)c(N)c2cccc(F)c2c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.35
CYP1A2 P05177 4/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 3/20 0.35
TSHR P16473 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
PIK3CA P42336 1/20 0.34
ACHE P22303 2/20 0.33
CYP2D6 P10635 2/20 0.33
TAAR1 Q96RJ0 1/20 0.32
PARP1 P09874 1/20 0.32
CD44 P16070 1/20 0.31
TYMS P04818 1/20 0.31
CYP2A6 P11509 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16029928 0.79 CYP2A6 (0.44) CYP3A4CYP1A2TSHRALDH1A1HPGD
SCHEMBL3675001 0.76 ALDH1A1 (0.47) CYP3A4CYP1A2TSHRALDH1A1KDM4E
SCHEMBL3674304 0.76 HKDC1 (0.42) CYP3A4CYP1A2TSHRALDH1A1HPGD
SCHEMBL3676167 0.72 ALDH1A1 (0.35) CYP3A4CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL5252035 0.71 ACHE (0.36) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL8197963 0.71 CYP3A4 (0.48) CYP3A4CYP1A2TSHRALDH1A1HPGD
SCHEMBL5605522 0.69 ALDH1A1 (0.50) CYP3A4CYP1A2TSHRALDH1A1HPGD
Ammonia Solution, Strong SCHEMBL16600069 0.69 CYP2A6 (0.42) CYP3A4CYP1A2TSHRALDH1A1HPGD
SCHEMBL31180772 0.69 ACHE (0.39) CYP3A4CYP1A2TSHRALDH1A1HPGD
SCHEMBL3679087 0.69 ACHE (0.39) CYP3A4CYP1A2TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed