Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672476 | 0.90 | MTOR (0.43) | MTORMRGPRX4S1PR1HDAC3HDAC1 | |
| SCHEMBL1947830 | 0.85 | PTGDR2 (0.55) | MRGPRX4LTB4R2 | |
| SCHEMBL3667571 | 0.82 | MGLL (0.42) | S1PR1TACR1LTB4R2THRATHRB | |
| SCHEMBL3668638 | 0.82 | MTOR (0.64) | MTORAOC3TACR1POLB | |
| SCHEMBL3666210 | 0.80 | FSHR (0.40) | MRGPRX4S1PR1HDAC3HDAC1HDAC2 | |
| SCHEMBL3671611 | 0.79 | PDK1 (0.54) | HDAC3HDAC1HDAC2TACR1PDK1 | |
| SCHEMBL3666332 | 0.78 | MTOR (0.47) | MTORTACR1POLB | |
| SCHEMBL3671391 | 0.76 | TACR1 (0.43) | MTORTMEM97SIGMAR1TACR1LTB4R2 | |
| SCHEMBL3666876 | 0.76 | ABHD6 (0.54) | MTORAOC3TACR1ALDH1A1THRA | |
| SCHEMBL3670884 | 0.76 | PTGDR2 (0.44) | S1PR1HDAC1ALDH1A1LTB4R2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |