Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 4/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671609 | 0.89 | MLYCD (0.52) | PDK1MLYCDMEN1KMT2ATACR1 | |
| SCHEMBL3670286 | 0.88 | HSD17B1 (0.45) | PDK1MLYCDMEN1KMT2ATACR1 | |
| SCHEMBL3666876 | 0.84 | ABHD6 (0.54) | PDK1MEN1KMT2ATACR1HSD17B2 | |
| SCHEMBL3668638 | 0.84 | MTOR (0.64) | MEN1KMT2ATACR1 | |
| SCHEMBL1947876 | 0.84 | PTGDR2 (0.64) | MLYCDMEN1KMT2ATACR1 | |
| SCHEMBL3667571 | 0.81 | MGLL (0.42) | PDK1MEN1KMT2ATACR1HSD17B2 | |
| SCHEMBL3666867 | 0.80 | HDAC6 (0.56) | PDK1MEN1KMT2ATACR1HDAC6 | |
| SCHEMBL3668839 | 0.80 | NR1H3 (0.53) | MEN1KMT2AHSD17B2HSD17B1HDAC4 | |
| SCHEMBL3672481 | 0.79 | MTOR (0.43) | PDK1TACR1HDAC3HDAC1HDAC2 | |
| SCHEMBL3671902 | 0.78 | LIPE (0.46) | PDK1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |