Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785507 | 0.82 | METAP1 (0.44) | MAPTALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL4608245 | 0.82 | CYP1A2 (0.48) | ALDH1A1PKMHPGDSMN1; SMN2MEN1 | |
| SCHEMBL6100903 | 0.81 | L3MBTL1 (0.37) | MAPTALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL9050785 | 0.78 | MAPK8 (0.64) | MAPTALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL4633510 | 0.77 | KMT2A (0.65) | MAPTALDH1A1NPC1TSHRHPGD | |
| SCHEMBL3672729 | 0.77 | KDM4E (0.37) | MAPTALDH1A1NPC1PTK2TSHR | |
| SCHEMBL10804734 | 0.77 | HPGD (0.41) | MAPTALDH1A1NPC1PKMHPGD | |
| SCHEMBL4607918 | 0.75 | KDM4E (0.36) | MAPTALDH1A1NPC1PTK2HPGD | |
| SCHEMBL14486887 | 0.75 | MAPT (0.37) | MAPTALDH1A1NPC1PKMHPGD | |
| SCHEMBL9533816 | 0.75 | KDM4E (0.36) | MAPTALDH1A1NPC1PTK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664058-B1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1664058-A1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | Sanofi-Aventis Deutschland GmbH (DE) | 2006-06-07 | — | — | EP | disclosed |
| EP-1513834-B1 | SUBSTITUTED THIOPHENES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC REAGENT, AND A MEDICAMENT CONTAINING THE SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005026173-A1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-03-24 | — | — | WO | disclosed |
| EP-1513834-A1 | SUBSTITUTED THIOPHENES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC REAGENT, AND A MEDICAMENT CONTAINING THE SAME | Aventis Pharma Deutschland GmbH (DE) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003101984-A1 | SUBSTITUTED THIOPHENES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC REAGENT, AND A MEDICAMENT CONTAINING THE SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | WO | disclosed |