Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12565652 | 0.91 | TSHR (0.42) | TSHRMAPK1MEN1KMT2AMGLL | |
| SCHEMBL14134498 | 0.87 | MEN1 (0.40) | TSHRCTHCBSTHPOMAPK1 | |
| SCHEMBL1932585 | 0.87 | MEN1 (0.40) | TSHRCTHCBSTHPOMAPK1 | |
| SCHEMBL9570301 | 0.84 | GPR84 (0.40) | PAMACHE | |
| SCHEMBL2192211 | 0.83 | TSHR (0.45) | TSHRMAPK1THRBMEN1KMT2A | |
| SCHEMBL7122301 | 0.83 | MEN1 (0.43) | TSHRMAPK1THRBMEN1KMT2A | |
| SCHEMBL14134695 | 0.82 | MEN1 (0.36) | TSHRMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL803309 | 0.82 | PAM (0.39) | TSHRCTHCBSTHPOMAPK1 | |
| SCHEMBL27978106 | 0.81 | TSHR (0.43) | TSHRMAPK1MEN1KMT2AMGLL | |
| SCHEMBL28250371 | 0.81 | TSHR (0.43) | TSHRMAPK1MEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200179257-A1 | CONDITIONING COMPOSITIONS CONTAINING CATIONIC COMPOUNDS, A SILANE COMPOUND AND SILICA PARTICLES AND METHODS FOR USE | L'OREAL (FR) | 2020-06-11 | — | — | US | claimed |
| US-20180055751-A1 | COMPOSITIONS COMPRISING AN ASSOCIATON OF CATIONIC COMPOUNDS, SILANE COMPOUNDS, ESTERS AND FATTY SUBSTANCES | L'OREAL (FR) | 2018-03-01 | — | — | US | claimed |
| US-9115289-B2 | Multibranched bioadhesive compounds and synthetic methods therefor | KENSEY NASH CORPORATION (US) | 2015-08-25 | — | — | US | claimed |
| US-20120029559-A1 | MULTIBRANCHED BIOADHESIVE COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KNC NER ACQUISITION SUB, INC. (US) | 2012-02-02 | — | — | US | claimed |
| EP-2393846-A1 | MULTIBRANCHED BIOADHESIVE COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KNC NER Acquisition Sub, Inc. (US) | 2011-12-14 | — | — | EP | claimed |
| WO-2010091298-A1 | MULTIBRANCHED BIOADHESIVE COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION (US) | 2010-08-12 | — | — | WO | claimed |
| US-7604924-B2 | Negative-working imageable elements and methods of use | EASTMAN KODAK COMPANY (US) | 2009-10-20 | — | — | US | claimed |
| US-20090252697-A1 | METHOD FOR PERMANENTLY RESHAPING KERATIN FIBERS WITH AN ACID PRE-TREATING COMPOSITION | L'OREAL S.A. (FR) | 2009-10-08 | — | — | US | claimed |
| US-20090111051-A1 | NEGATIVE-WORKING IMAGEABLE ELEMENTS AND METHODS OF USE | CITICORP NORTH AMERICA, INC., AS AGENT | 2009-04-30 | — | — | US | claimed |
| US-20050136687-A1 | Porous silica dielectric having improved etch selectivity towards inorganic anti-reflective coating materials for integrated circuit applications, and methods of manufacture | HONEYWELL INTERNATIONAL INC | 2005-06-23 | — | — | US | claimed |
| JP-5299300-A | — | — | None | — | — | JP | disclosed |
| EP-3246464-B1 | PAPER AND METHODS OF MAKING PAPER | KEMIRA OYJ (FI) | 2023-11-01 | — | — | EP | disclosed |
| US-11737964-B2 | Hair color toning compositions, methods of use, and kits | L'OREAL (FR) | 2023-08-29 | — | — | US | disclosed |
| US-11666521-B2 | Conditioning compositions containing cationic compounds, a silane compound and silica particles and methods for use | L'OREAL (FR) | 2023-06-06 | — | — | US | disclosed |
| US-20230099740-A1 | HAIR COLOR TONING COMPOSITIONS, METHODS OF USE, AND KITS | L'OREAL (FR) | 2023-03-30 | — | — | US | disclosed |
| US-6544686-B1 | Electrochemical performance; storage | ELECTRIC FUEL LIMITED (IL) | 2003-04-08 | — | — | US | disclosed |
| EP-0803553-B1 | Bleed control in ink-jet inks via aqueous phase separation | HEWLETT PACKARD CO (US) | 2000-01-12 | — | — | EP | disclosed |
| US-5700317-A | INK-JET INK SET INCLUDING FIRST INK COMPRISING COLORANT AND AQUEOUS VEHICLE INCLUDING POLYMER, SECOND INK COMPRISING COLORANT AND AQUEOUS VEHICLE INCLUDING SPECIES CAPABLE OF INDUCING PHASE SEPARATION IN EVENT OF CONTACT | HEWLETT-PACKARD COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0803553-A1 | Bleed control in ink-jet inks via aqueous phase separation | Hewlett-Packard Company (US) | 1997-10-29 | — | — | EP | disclosed |
| JP-H05299300-A | ELECTROLYTE OF ELECTROLYTIC CAPACITOR | NIPPON CHEMICON CORP | 1993-11-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737964-B2 | Hair color toning compositions, methods of use, and kits | CUTA, TAAR5, SHH | TSHR 392/4885CTH 867/4885CBS 1751/4885 |
| US-11666521-B2 | Conditioning compositions containing cationic compounds, a silane compound and silica particles and methods for use | KRT18, SGMS1, SGMS2 | TSHR 4724/4885CTH 1495/4885CBS 3094/4885 |
| US-20180055751-A1 | COMPOSITIONS COMPRISING AN ASSOCIATON OF CATIONIC COMPOUNDS, SILANE COMPOUNDS, ESTERS AND FATTY SUBSTANCES | FASN, SGMS1, KRT18 | TSHR 4861/4885CTH 1561/4885CBS 1872/4885 |
| US-20090252697-A1 | METHOD FOR PERMANENTLY RESHAPING KERATIN FIBERS WITH AN ACID PRE-TREATING COMPOSITION | KRT18, CUTA, COL14A1 | TSHR 4002/4885CTH 1333/4885CBS 3044/4885 |
| US-20230099740-A1 | HAIR COLOR TONING COMPOSITIONS, METHODS OF USE, AND KITS | CUTA, TAAR5, SHH | TSHR 392/4885CTH 867/4885CBS 1751/4885 |
| US-20200179257-A1 | CONDITIONING COMPOSITIONS CONTAINING CATIONIC COMPOUNDS, A SILANE COMPOUND AND SILICA PARTICLES AND METHODS FOR USE | KRT18, SGMS1, SGMS2 | TSHR 4724/4885CTH 1495/4885CBS 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.