SCHEMBL3673596

SCHEMBL3673596

C[Si](C)(C)Oc1ccc(C=O)cc1O[Si](C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.57
TSHR P16473 1/20 0.57
FDPS P14324 1/20 0.49
AOX1 Q06278 1/20 0.47
TRIM24 O15164 1/20 0.47
HPGD P15428 1/20 0.47
ALDH5A1 P51649 1/20 0.47
ABAT P80404 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TRIM33 Q9UPN9 1/20 0.47
TTR P02766 1/20 0.45
MAPT P10636 4/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A3 P47895 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30360257 1.00 ALDH1A1 (0.57) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL9677313 0.91 ALDH1A1 (0.72) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL28422136 0.83 ALDH1A1 (0.47) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL30360260 0.82 ALDH1A1 (0.50) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL36740 0.82 ALDH1A1 (0.50) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL29519519 0.80 TRPA1 (0.47) ALDH1A1TSHRHPGDTDP1TTR
SCHEMBL18035216 0.80 TRPA1 (0.47) ALDH1A1TSHRHPGDTDP1TTR
SCHEMBL28589373 0.79 ALDH1A1 (0.72) ALDH1A1TSHRFDPSAOX1TRIM24
Water SCHEMBL19810873 0.78 TRPA1 (0.46) ALDH1A1TSHRHPGDTDP1TTR
SCHEMBL7761025 0.77 ALDH1A1 (0.75) ALDH1A1TSHRFDPSAOX1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11512148-B2 Composition including multiple terminally functionalized polymers BRIDGESTONE CORPORATION (JP) 2022-11-29 US claimed
US-20200369791-A1 Composition Including Multiple Terminally Functionalized Polymers BRIDGESTONE CORPORATION (JP) 2020-11-26 US claimed
EP-2716702-B1 METHOD FOR PRODUCING RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2020-11-04 EP claimed
US-9447255-B2 Method for producing rubber composition BRIDGESTONE CORPORATION (JP) 2016-09-20 US claimed
US-20140187693-A1 METHOD FOR PRODUCING RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
US-20250361387-A1 RUBBER COMPOSITION FOR TIRES AND TIRE BRIDGESTONE CORPORATION (JP) 2025-11-27 US disclosed
EP-4653495-A1 RUBBER COMPOSITION AND CROSSLINKED MATERIAL Kuraray Co., Ltd. (JP) 2025-11-26 EP disclosed
EP-3882046-B1 RUBBER COMPOSITION, VULCANIZED RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2025-07-30 EP disclosed
EP-4541848-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2025-04-23 EP disclosed
EP-3882045-B1 RUBBER COMPOSITION, VULCANIZED RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2025-03-26 EP disclosed
WO-2025028543-A1 TIRE RUBBER COMPOSITION, TIRE VULCANIZED RUBBER, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-02-06 WO disclosed
WO-2024154753-A1 RUBBER COMPOSITION AND CROSSLINKED MATERIAL 株式会社クラレ 2024-07-25 WO disclosed
EP-2231719-B1 HYDROXYARYL FUNCTIONALIZED POLYMERS BRIDGESTONE CORP (JP) 2015-07-29 EP disclosed
US-20150141582-A1 Hydroxyaryl Functionalized Polymers BRIDGESTONE CORPORATION (JP) 2015-05-21 US disclosed
US-8871871-B2 Hydroxyaryl functionalized polymers BRIDGESTONE CORPORATION (JP) 2014-10-28 US disclosed
US-20140187693-A1 METHOD FOR PRODUCING RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2014-07-03 US disclosed
EP-2589611-A1 Hydroxyaryl functionalized polymers Bridgestone Corporation (JP) 2013-05-08 EP disclosed
US-20100286348-A1 HYDROXYARYL FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2010-11-11 US disclosed
EP-2231719-A2 HYDROXYARYL FUNCTIONALIZED POLYMERS Bridgestone Corporation (JP) 2010-09-29 EP disclosed
WO-2009086490-A2 HYDROXYARYL FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2009-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141582-A1 Hydroxyaryl Functionalized Polymers HAAO, HCAR3, VCL ALDH1A1 564/4885TSHR 3633/4885FDPS 490/4885
US-20100286348-A1 HYDROXYARYL FUNCTIONALIZED POLYMERS HAAO, HCAR3, VCL ALDH1A1 564/4885TSHR 3633/4885FDPS 490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.