Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CLTC | Q00610 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676167 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL3678465 | 0.79 | NR4A2 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL3670998 | 0.72 | ACHE (0.35) | ALDH1A1KDM4E | |
| SCHEMBL3674304 | 0.72 | HKDC1 (0.42) | HKDC1ALDH1A1BACE1 | |
| SCHEMBL3670402 | 0.72 | GABRA1 (0.35) | HKDC1GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL28275480 | 0.71 | ALDH1A1 (0.35) | GABRA1GABRB2PRNPALDH1A1CYP1B1 | |
| SCHEMBL3674645 | 0.70 | ALDH1A1 (0.35) | HKDC1GABRA1GABRB2ALDH1A1CYP1B1 | |
| SCHEMBL1293277 | 0.69 | GABRA1 (0.48) | GABRA1GABRB2PRNPALDH1A1 | |
| SCHEMBL6204770 | 0.69 | GABRA1 (0.39) | GABRA1GABRB2ALDH1A1BACE1 | |
| SCHEMBL28276708 | 0.68 | ALDH1A1 (0.35) | GABRA1GABRB2PRNPALDH1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |