SCHEMBL3674860

SCHEMBL3674860

C=C(C)COC(C)Sc1ccc(S(=O)(=O)c2ccc(SC(C)OCC(=C)C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 4/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 5/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MMP1 P03956 1/20 0.31
MMP13 P45452 1/20 0.31
ATM Q13315 1/20 0.30
ELANE P08246 1/20 0.30
DNMT1 P26358 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7575940 0.83 SMN1; SMN2 (0.36) ALDH1A1L3MBTL1LMNAGAANPSR1
SCHEMBL2153455 0.75 PKM (0.44) PKMMAPTPOLBALDH1A1L3MBTL1
SCHEMBL3678272 0.72 PKM (0.36) PKMMAPTPOLBALDH1A1LMNA
SCHEMBL7572469 0.72 SMN1; SMN2 (0.33) L3MBTL1LMNAGAANPSR1SMN1; SMN2
SCHEMBL14351823 0.70 GAA (0.43) PKMMAPTPOLBALDH1A1LMNA
SCHEMBL20237261 0.70 PKM (0.41) PKMMAPTPOLBALDH1A1L3MBTL1
SCHEMBL3674937 0.69 MAPT (0.37) PKMMAPTPOLBALDH1A1LMNA
SCHEMBL11168992 0.66 ALDH1A1 (0.38) PKMPOLBALDH1A1KMT2AGAA
SCHEMBL11168390 0.66 POLB (0.36) PKMMAPTPOLBALDH1A1LMNA
SCHEMBL10871424 0.66 LMNA (0.48) PKMMAPTPOLBALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8804245-B2 Stacked diffraction optical element including an optical element made of organic-inorganic composite resin material CANON KABUSHIKI KAISHA (JP) 2014-08-12 US disclosed
US-8344094-B2 Optical material and optical element CANON KABUSHIKI KAISHA (JP) 2013-01-01 US disclosed
US-20120200925-A1 ORGANIC-INORGANIC COMPOSITE RESIN COMPOSITION, ORGANIC-INORGANIC COMPOSITE RESIN MATERIAL, OPTICAL ELEMENT, AND STACKED DIFFRACTION OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2012-08-09 US disclosed
US-20100076106-A1 OPTICAL MATERIAL AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2010-03-25 US disclosed