SCHEMBL7575940

SCHEMBL7575940

C=C(C)COC(C)Sc1ccc(Sc2ccc(SC(C)OCC(=C)C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 3/20 0.36
HPGD P15428 4/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
THRB P10828 1/20 0.33
SLC6A4 P31645 1/20 0.31
NR1H2 P55055 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7572469 0.87 SMN1; SMN2 (0.33) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL3674860 0.83 PKM (0.36) SMN1; SMN2LMNAGAANPSR1L3MBTL1
SCHEMBL3107707 0.77 SMN1; SMN2 (0.40) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL21143038 0.71 HPGD (0.40) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL3687010 0.71 SMN1; SMN2 (0.50) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL2780451 0.71 HPGD (0.38) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL8092172 0.69
SCHEMBL3098494 0.67 LMNA (0.32) SMN1; SMN2LMNAHPGD
SCHEMBL8752803 0.67 NR1H2 (0.39) LMNANR1H2
SCHEMBL477411 0.67 NR1H2 (0.39) LMNAHPGDNR1H2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7206944-A None JP disclosed
EP-0795765-B1 Photopolymerizable composition and transparent cured product thereof TOKUYAMA CORP (JP) 2002-09-25 EP disclosed
US-5880170-A TRANSPARENT LENSES FORMED BY CURING TOKUYAMA CORPORATION (JP) 1999-03-09 US disclosed
EP-0795765-A2 Photopolymerizable composition and transparent cured product thereof TOKUYAMA CORPORATION (JP) 1997-09-17 EP disclosed
JP-H07206944-A COMPOSITION FOR FORMING PLASTIC LENS AND PLASTIC LENS PRODUCED BY USING THE COMPOSITION MITSUBISHI RAYON CO LTD 1995-08-08 JP disclosed