Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13177764 | 0.87 | HPRT1 (0.48) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL12737099 | 0.87 | TSHR (0.54) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL4800396 | 0.87 | PTPN22 (0.54) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL30944688 | 0.84 | DNMT1 (0.47) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL28386537 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL367587 | 0.84 | DNMT1 (0.47) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL13207448 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL14182479 | 0.83 | HSD17B10 (0.41) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL20256051 | 0.82 | MAPT (0.40) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL369163 | 0.82 | MAPT (0.81) | ALDH1A1TDP1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673376-B2 | Laminate | DAIKIN INDUSTRIES. LTD. (JP) | 2023-06-13 | — | — | US | disclosed |
| US-9951067-B2 | Optically active α-trifluoromethyl-β-amino acid derivative production method | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-04-24 | — | — | US | disclosed |
| US-9938204-B2 | Intermolecular C-H silylation of unactivated arenes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-10 | — | — | US | disclosed |
| US-20180029993-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-01 | — | — | US | disclosed |
| US-20170283411-A1 | Optically Active a-Trifluoromethyl-B-Amino Acid Derivative Production Method | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-10-05 | — | — | US | disclosed |
| US-9533928-B2 | Catalytic anti-markovnikov oxidation and hydration of olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-01-03 | — | — | US | disclosed |
| WO-2016198836-A1 | ASYMMETRIC ADDITION REACTIONS | ISIS INNOVATION LIMITED (GB) | 2016-12-15 | — | — | WO | disclosed |
| US-20160200639-A1 | INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-07-14 | — | — | US | disclosed |
| US-20150299073-A1 | CATALYTIC ANTI-MARKOVNIKOV OXIDATION AND HYDRATION OF OLEFINS | CALIFORNIA INST OF TECHN (US) | 2015-10-22 | — | — | US | disclosed |
| US-9120732-B2 | Catalytic anti-markovnikov oxidation and hydration of olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-01 | — | — | US | disclosed |
| US-20080139822-A1 | Novel optically active biaryl phosphorus compound and production process thereof | MAXWELL TECHNOLOGIES, INC. | 2008-06-12 | — | — | US | disclosed |
| US-7301039-B2 | Process for preparing cationic rhodium complexes | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-11-27 | — | — | US | disclosed |
| WO-2007123941-A2 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2007-11-01 | — | — | WO | disclosed |
| US-20070093660-A1 | Method for the production of statins | RATIOPHARM GMBH (DE) | 2007-04-26 | — | — | US | disclosed |
| US-7173138-B2 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-06 | — | — | US | disclosed |
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
| US-20070004928-A1 | Process for preparing cationic rhodium complexes | RAMSDEN JAMES A | 2007-01-04 | — | — | US | disclosed |
| WO-2006122644-A2 | METHOD FOR THE PRODUCTION OF STATINS | RATIOPHARM GMBH (DE) | 2006-11-23 | — | — | WO | disclosed |
| US-20040110960-A1 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
| EP-0850945-B1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200639-A1 | INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES | CCNH, CTTN, CCRL2 | ALDH1A1 3641/4885CYP2A6 719/4885HSD17B10 748/4885 |
| US-20070004928-A1 | Process for preparing cationic rhodium complexes | RDX, RXFP1, SDF4 | ALDH1A1 4742/4885CYP2A6 4647/4885HSD17B10 4267/4885 |
| US-20170283411-A1 | Optically Active a-Trifluoromethyl-B-Amino Acid Derivative Production Method | BCAT1, BCAT2, ALAD | ALDH1A1 563/4885CYP2A6 1810/4885HSD17B10 3544/4885 |
| US-20070093660-A1 | Method for the production of statins | HMGCR, CYP11A1, CYP51A1 | ALDH1A1 673/4885CYP2A6 65/4885HSD17B10 23/4885 |
| US-20080139822-A1 | Novel optically active biaryl phosphorus compound and production process thereof | PHOSPHO1, DHRS9, HDHD5 | ALDH1A1 2036/4885CYP2A6 1282/4885HSD17B10 468/4885 |
| US-20150299073-A1 | CATALYTIC ANTI-MARKOVNIKOV OXIDATION AND HYDRATION OF OLEFINS | ADH1A, ADH5, ADH1C | ALDH1A1 225/4885CYP2A6 61/4885HSD17B10 103/4885 |
| US-20040110960-A1 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | OGG1, HPD, HPGD | ALDH1A1 2725/4885CYP2A6 790/4885HSD17B10 1244/4885 |
| US-20180029993-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE | ALAD, GRHPR, ME1 | ALDH1A1 1143/4885CYP2A6 112/4885HSD17B10 374/4885 |
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | MPI, ITPA, DCPS | ALDH1A1 1727/4885CYP2A6 1875/4885HSD17B10 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.