Atrazine

Atrazine

SCHEMBL367604

CC(N)=O.CCNc1nc(Cl)nc(NC(C)C)n1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.58
TDP1 Q9NUW8 2/20 0.58
LMNA P02545 1/20 0.58
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
POLB P06746 1/20 0.48
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MCL1 Q07820 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propazine SCHEMBL9379274 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Propazine SCHEMBL9092745 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Atrazine SCHEMBL36936 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Atrazine SCHEMBL4306269 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Atrazine SCHEMBL1516439 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Propazine SCHEMBL29366712 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Atrazine SCHEMBL9117361 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Atrazine SCHEMBL29353679 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Atrazine SCHEMBL20723465 0.89 GAA (0.73) GAATDP1LMNAHTTL3MBTL1
Atrazine SCHEMBL20723443 0.87 GAA (0.70) GAATDP1LMNAHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1531670-B1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2015-12-09 EP disclosed
US-8551918-B2 Herbicidal composition SYNGENTA CROP PROTECTION LLC (US) 2013-10-08 US disclosed
US-8097561-B2 Herbicidal composition SYNGENTA CROP PROTECTION, INC. (US) 2012-01-17 US disclosed
US-20070197387-A1 Herbicidal Composition SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 US disclosed
EP-1689227-A2 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2006-08-16 EP disclosed
EP-1531670-A4 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-11-23 EP disclosed
US-20050233907-A1 Herbicidal composition SYNGENTA CROP PROTECTION AG (CH) 2005-10-20 US disclosed
WO-2005055716-A2 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-06-23 WO disclosed
EP-1531670-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2005-05-25 EP disclosed
WO-2003105587-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2003-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233907-A1 Herbicidal composition ADH5, ADH1C, AQP3 GAA 1060/4885TDP1 4359/4885LMNA 3158/4885
US-20070197387-A1 Herbicidal Composition DDT, HDHD5, DERL1 GAA 652/4885TDP1 1427/4885LMNA 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.