Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.72 |
| ▸ | FABP3 | P05413 | 7/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3676569 | 1.00 | CA1 (0.72) | CA1FABP3FAAHTERTGMNN | |
| Potassium Ion SCHEMBL28650547 | 0.89 | CA1 (0.91) | CA1MAPT | |
| Potassium Ion SCHEMBL10339651 | 0.89 | CA1 (0.91) | CA1MAPT | |
| SCHEMBL15022016 | 0.87 | CA1 (0.95) | CA1MAPT | |
| SCHEMBL15022951 | 0.87 | CA1 (0.95) | CA1MAPT | |
| SCHEMBL15022175 | 0.87 | CA1 (0.95) | CA1MAPT | |
| Potassium Ion SCHEMBL29948033 | 0.87 | CA1 (0.95) | CA1NPSR1 | |
| SCHEMBL8978718 | 0.85 | CA1 (0.96) | CA1MAPTNPSR1 | |
| Silver SCHEMBL17797181 | 0.85 | CA1 (0.91) | CA1MAPT | |
| SCHEMBL8586952 | 0.85 | CA1 (0.96) | CA1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655604-B2 | Process of hydraulic fracturing using a viscoelastic wellbore fluid | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2010-02-02 | — | — | US | disclosed |
| US-20090270282-A1 | A reversibly thickenener for water-based wellbore fluids also soluble in organic and aqueous fluids comprising a branched long-chain carboxylic acid, sulfate or sulfonate or salt thereof; aqueous viscoelastic solutions via micellar aggregation; hydrophobic; broken gel mixes with hydrocarbon in well | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2009-10-29 | — | — | US | disclosed |
| US-7576043-B2 | Viscoelastic wellbore fluid comprising an anionic surfactant | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| US-20070197404-A1 | having branched aliphatic chains used as reversible well bore fluid thickeners to recover hydrocarbon oil and gas; oil soluble; soluble in both organic and aqueous fluids; high speed breakdown of viscoelastic sols | JONES TIMOTHY G J | 2007-08-23 | — | — | US | disclosed |
| US-7196041-B2 | Surfactant comprising alkali metal salt of 2-methyl oleic acid or 2-ethyl oleic acid | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-20040053789-A1 | Surfactant | SHLUMBERGER TECHNOLOGY CORPORATION | 2004-03-18 | — | — | US | disclosed |
| WO-2002011873-A1 | SURFACTANT | SOFITECH N.V. (BE) | 2002-02-14 | — | — | WO | disclosed |