Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 4/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 4/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 4/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 4/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661178 | 0.94 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4661142 | 0.87 | VNN1 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL682183 | 0.86 | HDAC3 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7615412 | 0.86 | HDAC3 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7620776 | 0.86 | HDAC3 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13120804 | 0.84 | HDAC1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3673780 | 0.84 | HDAC3 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9663825 | 0.82 | LTB4R (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9056155 | 0.80 | S1PR2 (0.46) | HDAC1LTB4RMEN1KMT2A | |
| SCHEMBL9056380 | 0.79 | MAPT (0.40) | FFAR1KMT2AACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261933-A1 | METHOD FOR PREPARING CARBOXYLIC ACID COMPOUND | KOWA COMPANY, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261933-A1 | METHOD FOR PREPARING CARBOXYLIC ACID COMPOUND | KOWA COMPANY, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261933-A1 | METHOD FOR PREPARING CARBOXYLIC ACID COMPOUND | KOWA COMPANY, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| EP-1627866-B1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2008-12-24 | — | — | EP | disclosed |
| EP-2003112-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID COMPOUND | Kowa Company, Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
| EP-2003112-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID COMPOUND | Kowa Company, Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-7109242-B2 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1627866-A1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Company Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261933-A1 | METHOD FOR PREPARING CARBOXYLIC ACID COMPOUND | HCAR1, HAO1, HCAR2 | HDAC3 2413/4885HDAC4 2500/4885HDAC1 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.