Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366816 | 0.92 | KMT2A (0.37) | MEN1POLBKMT2AALDH1A1MAPK1 | |
| SCHEMBL366618 | 0.92 | MEN1 (0.37) | ACHECYP2D6MEN1POLBKMT2A | |
| SCHEMBL366080 | 0.91 | ALDH1A1 (0.38) | ACHEMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL365114 | 0.87 | ALDH1A1 (0.34) | CYP2D6MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL365169 | 0.87 | ACHE (0.41) | ACHECYP2D6KCNH2 | |
| SCHEMBL365925 | 0.86 | ACHE (0.42) | ACHECYP2D6KCNH2 | |
| SCHEMBL366915 | 0.86 | PSEN1 (0.37) | MEN1POLBKMT2AALDH1A1MAPK1 | |
| SCHEMBL365986 | 0.85 | KMT2A (0.38) | MEN1POLBKMT2AALDH1A1MAPK1 | |
| SCHEMBL366531 | 0.83 | MEN1 (0.36) | ACHEMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL367690 | 0.81 | MEN1 (0.43) | ACHECYP2D6KCNH2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |