Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366618 | 0.92 | MEN1 (0.37) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL366816 | 0.92 | KMT2A (0.37) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL365769 | 0.86 | LTB4R (0.39) | KMT2AMEN1ALDH1A1CNR2LMNA | |
| SCHEMBL365837 | 0.85 | CNR2 (0.37) | KMT2AMEN1ALDH1A1CNR2LMNA | |
| SCHEMBL367691 | 0.85 | ACHE (0.40) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL365114 | 0.84 | ALDH1A1 (0.34) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL366080 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL365985 | 0.79 | MEN1 (0.46) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL365593 | 0.78 | MRGPRX4 (0.39) | LTB4RLTB4R2 | |
| SCHEMBL366851 | 0.78 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1POLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |