Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366080 | 0.91 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL365006 | 0.87 | LTB4R (0.35) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL365216 | 0.85 | ACHE (0.36) | MEN1KMT2AMAPK1KDM4ENPC1 | |
| SCHEMBL366816 | 0.84 | KMT2A (0.37) | MEN1KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL367691 | 0.83 | ACHE (0.40) | MEN1KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL365114 | 0.80 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL366530 | 0.79 | CYP11B1 (0.35) | MEN1KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL365189 | 0.78 | ACHE (0.37) | ALDH1A1ACHECYP11B1CYP11B2SCN9A | |
| SCHEMBL366612 | 0.76 | ACHE (0.38) | KMT2AACHECYP11B1CYP11B2SCN9A | |
| SCHEMBL366618 | 0.76 | MEN1 (0.37) | MEN1KMT2AALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |