Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL10618785 | 0.82 | PARP10 (0.71) | LTA4HTSHRPARP10ALDH1A1HPGD | |
| Diphenylether SCHEMBL8165466 | 0.82 | PARP10 (0.71) | LTA4HTSHRPARP10ALDH1A1HPGD | |
| Diphenylether SCHEMBL360280 | 0.82 | LTA4H (0.75) | LTA4HTSHRPARP10HPGDSMN1; SMN2 | |
| Diphenylether SCHEMBL5606885 | 0.82 | LTA4H (0.75) | LTA4HTSHRPARP10HPGDSMN1; SMN2 | |
| Diphenylether SCHEMBL1965337 | 0.82 | LTA4H (0.75) | LTA4HTSHRPARP10HPGDSMN1; SMN2 | |
| SCHEMBL2835202 | 0.81 | ALDH1A1 (0.65) | TSHRPARP10ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28650509 | 0.80 | PARP10 (0.57) | LTA4HTSHRPARP10HPGDSMN1; SMN2 | |
| Diphenylether SCHEMBL28643061 | 0.80 | PARP10 (0.68) | LTA4HTSHRPARP10ALDH1A1HPGD | |
| Diphenylether SCHEMBL457909 | 0.79 | LTA4H (0.55) | LTA4HTSHRPARP10ALDH1A1KDM4E | |
| Diphenylether SCHEMBL28218624 | 0.79 | PARP10 (0.61) | LTA4HTSHRPARP10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235092-A1 | COATED POLYOXYMETHYLENES | BASF SE (DE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009092698-A1 | COATED POLYOXYMETHYLENES | BASF SE (DE) | 2009-07-30 | — | — | WO | disclosed |