Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600787 | 0.86 | PTGDR2 (0.41) | AKR1B1LTB4RPTGDR2TP53ALOX15 | |
| SCHEMBL10424599 | 0.86 | AKR1B1 (0.43) | AKR1B1LTB4RPTGDR2KEAP1NFE2L2 | |
| Carbamic Acid SCHEMBL9006901 | 0.82 | ALOX5 (0.42) | LTB4RKEAP1TP53ALOX15MAPK1 | |
| SCHEMBL1709256 | 0.81 | — | — | |
| Carbamic Acid SCHEMBL10511096 | 0.81 | ALOX5 (0.41) | LTB4RTP53ALOX15MAPK1KMT2A | |
| SCHEMBL11636866 | 0.81 | KEAP1 (0.40) | AKR1B1LTB4RPTGDR2KEAP1NFE2L2 | |
| SCHEMBL5057664 | 0.81 | KMT2A (0.46) | AKR1B1PTGDR2PTGS2KEAP1NFE2L2 | |
| SCHEMBL6065611 | 0.80 | LTB4R (0.51) | LTB4RHSD17B10ALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL29003993 | 0.79 | KEAP1 (0.34) | LTB4RKEAP1ALDH1A1ALOX5 | |
| SCHEMBL10888140 | 0.78 | LTB4R (0.43) | LTB4RPTGDR2TP53ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787579-B2 | Sensors and separation based on molecular recognition via electropolymerization and colloidal layer templates | UNIVERSITY OF HOUSTON SYSTEM (US) | 2020-09-29 | — | — | US | disclosed |
| CN-107216445-B | Nano composite and preparation method and application thereof | 南京大学 | 2020-02-21 | — | — | CN | disclosed |
| US-20140349176-A1 | ADDITIVE FOR ELECTROLYTE, ELECTROLYTE AND RECHARGEABLE LITHIUM BATTERY | SAMSUNG SDI CO., LTD. (KR) | 2014-11-27 | — | — | US | disclosed |
| US-20120263922-A1 | SENSORS AND SEPARATION BASED ON MOLECULAR RECOGNITION VIA ELECTROPOLYMERIZATION AND COLLOIDAL LAYER TEMPLATES | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2012-10-18 | — | — | US | disclosed |
| WO-2012009239-A2 | SENSORS AND SEPARATION BASED ON MOLECULAR RECOGNITION VIA ELECTROPOLYMERIZATION AND COLLOIDAL LAYER TEMPLATES | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2012-01-19 | — | — | WO | disclosed |
| US-7495020-B2 | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders | MERCK & CO., INC. (US) | 2009-02-24 | — | — | US | disclosed |
| US-7321012-B2 | Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom | THE UNIVERSITY OF CONNECTICUT (US) | 2008-01-22 | — | — | US | disclosed |
| US-7217295-B2 | Use of soluble conductive polymers for treating human keratin fibers | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| US-20060237696-A1 | Composition comprising at least one electrophilic monomer and at least one conductive polymer, and cosmetic processes for treating keratin fibers | L'OREAL S.A. (FR) | 2006-10-26 | — | — | US | disclosed |
| US-7091230-B2 | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders | MERCK & CO., INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20030171588-A1 | 1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof | LION BIOSCIENCE AG (DE) | 2003-09-11 | — | — | US | disclosed |
| EP-1301517-A1 | THIENOPYRROLIDINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-16 | — | — | EP | disclosed |
| US-6528653-B2 | E.g., 4,6-dihydro 4-(heterocyclic ring-methylene)thieno(2,3-b) pyrrolidin-5-one derivatives; tumor necrosis factor ) inhibitors; anticarcinogenic, -proliferative and -arthritic agents; Alzheimer's disease; cardiovascular disorders | HOFFMANN-LA ROCHE, INC. | 2003-03-04 | — | — | US | disclosed |
| WO-2002064094-A2 | 2-ARYLOXY-2-ARYLALKANOIC ACIDS FOR DIABETES AND LIPID DISORDERS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| US-20020028841-A1 | Thienopyrrolidinones | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | US | disclosed |
| WO-2002002567-A1 | THIENOPYRROLIDINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-10 | — | — | WO | disclosed |
| US-6048875-A | CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS | ADIR ET COMPAGNIE (FR) | 2000-04-11 | — | — | US | disclosed |
| US-5536573-A | FOR MULTILAYER THIN FILMS CONTAINING LAYERS OF DIFFERENT CONDUCTING POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1996-07-16 | — | — | US | disclosed |
| US-5518767-A | P-DOPED CONJUGATED POLYMER MONOLAYER WITH POLYANION BOUND ELECTROSTATICALLY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1996-05-21 | — | — | US | disclosed |
| WO-1995002251-A2 | MOLECULAR SELF-ASSEMBLY OF ELECTRICALLY CONDUCTIVE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171588-A1 | 1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof | BRD4, BICRA, HDAC6 | AKR1B1 4552/4885LTB4R 3146/4885PTGDR2 2837/4885 |
| US-20020028841-A1 | Thienopyrrolidinones | TNF, TYMP, TNFRSF1A | AKR1B1 1478/4885LTB4R 172/4885PTGDR2 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.