SCHEMBL5149151

SCHEMBL5149151

Cc1cc(C(O)(c2ccc(Cl)cc2)C(F)(F)F)ccc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.45
AR P10275 1/20 0.45
ESR2 Q92731 1/20 0.45
TSHR P16473 5/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPK1 P28482 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP3A4 P08684 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
NR3C1 P04150 2/20 0.37
NPC1 O15118 1/20 0.36
ATM Q13315 1/20 0.36
ALOX15 P16050 1/20 0.35
S100B P04271 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701086 0.84 ESR1 (0.43) ESR1ARESR2TSHRHIF1A
SCHEMBL5155967 0.81 CCR6 (0.41) ESR1ARESR2MAPK1SMN1; SMN2
SCHEMBL5151919 0.81 ESR1 (0.41) ESR1ARESR2TSHRHIF1A
SCHEMBL3678693 0.80 TSHR (0.61) TSHRMEN1KMT2AMAPK1HIF1A
SCHEMBL5154470 0.78 ESR1 (0.40) ESR1ARESR2TSHRMEN1
SCHEMBL5155430 0.77 PTGS1 (0.40) ESR1ARESR2TSHRMEN1
SCHEMBL5155426 0.77 PTGS1 (0.40) ESR1ARESR2TSHRMEN1
SCHEMBL5154597 0.77 CCR6 (0.41) ESR1ARESR2TSHRMEN1
SCHEMBL5155437 0.77 PTGS1 (0.40) ESR1ARESR2TSHRMEN1
SCHEMBL7101194 0.77 SMN1; SMN2 (0.55) ESR1ARESR2TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US disclosed
EP-1671941-A1 SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent L3MBTL1, L3MBTL3, L3MBTL4 ESR1 4327/4885AR 3106/4885ESR2 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.