Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | RECQL | P46063 | 3/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | ESR1 | P03372 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | HTR2A | P28223 | 2/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935287 | 1.00 | ALOX15 (0.73) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL7937186 | 1.00 | ALOX15 (0.73) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL31488529 | 1.00 | ALOX15 (0.73) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL3818 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL29350884 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL29355090 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL13906133 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL29434238 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL135976 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL57083 | 0.84 | ALOX15 (0.76) | ALOX15ALOX12KDM4ERECQLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111642575-A | Oily system containing 3, 4-dihydroxy phenethyl alcohol, preparation method and application | 杭州唯铂莱生物科技有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-111233631-A | Method for preparing 3, 4-dihydroxy phenethyl alcohol | 辽宁东科药业有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-115652458-A | Antibacterial blend fiber and preparation method thereof | 杭州唯铂莱生物科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115010583-A | Method for synthesizing hydroxytyrosol by simulating enzyme catalytic reaction | 四川大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-114507633-A | Temperature-sensitive recombinant strain for producing 3, 4-dihydroxy phenethyl alcohol and application thereof | 南京合谷生命生物科技有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114350717-A | Method for preparing 3, 4-dihydroxy phenethyl alcohol by using biological enzyme catalysis | 南京合谷生命生物科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-3225616-A1 | ALPHA-ASARY-LALDEHYDE ESTER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Northwest University (CN) | 2017-10-04 | — | — | EP | disclosed |
| CN-106928030-A | The method that hydroxytyrosol is prepared using organo-metallic compound | 广州南沙龙沙有限公司 | 2017-07-07 | — | — | CN | disclosed |
| US-20170152224-A1 | NOVEL PROSTAMIDES FOR THE TREATMENT OF GLAUCOMA AND RELATED DISEASES | ALLERGAN, INC. | 2017-06-01 | — | — | US | disclosed |
| CN-103080056-A | Method for preparing hydroxytyrosol by using organic metal compound | LONZA AG | 2013-05-01 | — | — | CN | disclosed |
| WO-2012006783-A1 | PROCESS FOR PRODUCTION OF HYDROXYTYROSOL USING ORGANOMETALLIC COMPOUNDS | LONZA LTD (CH) | 2012-01-19 | — | — | WO | disclosed |
| US-20020019531-A1 | Indoles | EISAI CO., LTD. | 2002-02-14 | — | — | US | disclosed |
| US-6248573-B1 | SULFONYLATING OR HALOGENATING A (S)-1-PHENYL-2-PROPANOL DERIVATIVE TO PRODUCE (S)-1-PHENYL-2-SUBSTITUTED PROPANE DERIVATIVE; CHEMICAL INTERMEDIATE FOR SYNTHESIS OF ANTIOBESITY DRUG | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0976732-A1 | 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5902900-A | OPTICAL PURITY, USE AS ANTI-OBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| US-5679557-A | Process of asymmetrically reducing 1-phenyl-2-oxo-propane derivatives with microorganisms | DAICEL CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0627397-B1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEM (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5508461-A | ANTIOBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0627397-A1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4212645-A | Hair dyeing composition containing an aryldiamine and a substituted catechol | LEVER BROTHERS COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019531-A1 | Indoles | INMT, MUSK, MB | ALOX15 2990/4885ALOX12 3594/4885KDM4E 927/4885 |
| US-20170152224-A1 | NOVEL PROSTAMIDES FOR THE TREATMENT OF GLAUCOMA AND RELATED DISEASES | PTGIS, PTGIR, PTGS1 | ALOX15 86/4885ALOX12 85/4885KDM4E 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.