Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | RECQL | P46063 | 3/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | ESR1 | P03372 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.76 |
| ▸ | HTR2A | P28223 | 2/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nordihydroguaiaretic Acid SCHEMBL135976 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL29355090 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL3818 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL340070 | 0.86 | GABRA1 (0.64) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL13906133 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL29434237 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL29350884 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL29434238 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL7935287 | 0.84 | ALOX15 (0.73) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL31488529 | 0.84 | ALOX15 (0.73) | ALOX15ALOX12KDM4ERECQLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202474-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2019-02-12 | — | — | US | claimed |
| US-20170073443-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (US) | 2017-03-16 | — | — | US | claimed |
| CN-106413754-A | Dopa decarboxylase inhibitor compositions | 纽罗德姆有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-103257137-A | Method of determining content of methyl ethyl ketone peroxide in workplace air through UV spectrophotometer | PONY TESTING INTERNAT GROUP | 2013-08-21 | — | — | CN | claimed |
| US-11685715-B2 | Antimicrobial compounds and nanostructures | THE BOEING COMPANY (US) | 2023-06-27 | — | — | US | disclosed |
| US-20230183428-A1 | CATECHOL FUNCTIONAL ORGANOPOLYSILOXANE, METHOD FOR PRODUCING SAME, AND POWDER TREATMENT AGENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-06-15 | — | — | US | disclosed |
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2023010282-A1 | PROCESS FOR PRODUCTION OF SUBSTITUTED OR UNSUBSTITUTED CATECHOL O, O-DIACETIC ACID ESTERS | RHODIA OPERATIONS (FR) | 2023-02-09 | — | — | WO | disclosed |
| US-11358985-B2 | Tripeptide compound, preparation method therefor, and application thereof | NORTHWEST UNIVERSITY (CN) | 2022-06-14 | — | — | US | disclosed |
| US-11174227-B2 | Antimicrobial compounds and nanostructures | THE BOEING COMPANY (US) | 2021-11-16 | — | — | US | disclosed |
| US-11078233-B2 | Tripeptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| EP-0261977-A2 | Catechol derivatives, and preventive and remedial preparations for regressive disorders in the central nervous system | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-03-30 | — | — | EP | disclosed |
| EP-0076221-B1 | PROCESS FOR THE ETHERIFICATION OF PHENOLS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-02 | — | — | EP | disclosed |
| EP-0037353-B1 | PROCESS FOR THE ETHERIFICATION OF PHENOLS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-06-08 | — | — | EP | disclosed |
| EP-0076221-A1 | Process for the etherification of phenols | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-04-06 | — | — | EP | disclosed |
| EP-0046719-A1 | Process for the etherification of phenols | RHONE-POULENC INDUSTRIES (FR) | 1982-03-03 | — | — | EP | disclosed |
| EP-0037353-A1 | Process for the etherification of phenols | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-10-07 | — | — | EP | disclosed |
| US-4212645-A | Hair dyeing composition containing an aryldiamine and a substituted catechol | LEVER BROTHERS COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-3979415-A | Method of preparation of sulfonated, dialkyl-substituted benzodioxoles | TEXACO INC. (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685715-B2 | Antimicrobial compounds and nanostructures | MPO, POLI, POLN | ALOX15 4036/4885ALOX12 4182/4885KDM4E 2703/4885 |
| US-11078233-B2 | Tripeptide epoxy ketone protease inhibitors | PREP, CTRL, ENPEP | ALOX15 446/4885ALOX12 788/4885KDM4E 353/4885 |
| US-11358985-B2 | Tripeptide compound, preparation method therefor, and application thereof | VIP, PREP, ACE | ALOX15 518/4885ALOX12 757/4885KDM4E 4263/4885 |
| US-11174227-B2 | Antimicrobial compounds and nanostructures | MPO, POLI, POLN | ALOX15 4036/4885ALOX12 4182/4885KDM4E 2703/4885 |
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | PPID, PPIF, PPIL1 | ALOX15 1176/4885ALOX12 1255/4885KDM4E 4072/4885 |
| US-20230183428-A1 | CATECHOL FUNCTIONAL ORGANOPOLYSILOXANE, METHOD FOR PRODUCING SAME, AND POWDER TREATMENT AGENT | COMT, MAN2B1, FANCD2 | ALOX15 2666/4885ALOX12 1787/4885KDM4E 2759/4885 |
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | DNPEP, PEPD, ANPEP | ALOX15 3191/4885ALOX12 3343/4885KDM4E 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.