Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 4/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451266 | 0.75 | — | — | |
| SCHEMBL15902275 | 0.73 | — | — | |
| SCHEMBL28247944 | 0.70 | FABP4 (0.33) | — | |
| SCHEMBL252263 | 0.69 | DHODH (0.45) | HCAR2DHODH | |
| SCHEMBL168735 | 0.67 | PYGM (0.35) | DHODHPYGM | |
| SCHEMBL1428318 | 0.67 | PYGM (0.35) | DHODHPYGM | |
| SCHEMBL11430568 | 0.67 | FFAR3 (0.36) | PYGMCYP1A2 | |
| SCHEMBL1286030 | 0.67 | PYGM (0.35) | DHODHPYGM | |
| SCHEMBL2296442 | 0.67 | — | — | |
| SCHEMBL17024326 | 0.62 | DHODH (0.41) | HCAR2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2025-02-27 | — | — | US | disclosed |
| EP-4452929-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | Immunic AG (DE) | 2024-10-30 | — | — | EP | disclosed |
| CN-118382610-A | DHODH inhibitors containing carboxylic acid bioisosteres | 埃慕尼克股份公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-110038575-B | Method for preparing specific selective hydrogenation catalysts by kneading and impregnation | IFP 新能源公司 | 2023-10-10 | — | — | CN | disclosed |
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |
| EP-3559165-B1 | SELECTIVE HYDROGENATION PROCESS WITH A NICKEL BASED CATALYST PREPARED BY AN ADDITIVE HAVING A CARBOXYLIC ACID FUNCTION | IFP ENERGIES NOW (FR) | 2022-09-14 | — | — | EP | disclosed |
| US-11439994-B2 | Method for the hydrogenation of aromatics using a nickel-based catalyst | IFP Energies Nouvelles (FR) | 2022-09-13 | — | — | US | disclosed |
| US-10927310-B2 | Selective hydrogenation method using a nickel-based catalyst produced using an additive comprising a carboxylic acid function | IFP Energies Nouvelles (FR) | 2021-02-23 | — | — | US | disclosed |
| US-20210031179-A1 | METHOD FOR THE HYDROGENATION OF AROMATICS USING A NICKEL-BASED CATALYST | IFP Energies Nouvelles (FR) | 2021-02-04 | — | — | US | disclosed |
| EP-2093214-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| CN-100462352-C | Novel compounds useful as anti-inflammatory, immunomodulatory and antiproliferative agents | 4SC AG (DE) | 2009-02-18 | — | — | CN | disclosed |
| US-7423057-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2008-09-09 | — | — | US | disclosed |
| US-7176241-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-20060199856-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4 SC AG (DE) | 2006-09-07 | — | — | US | disclosed |
| CN-1525954-A | Novel compounds useful as anti-inflammatory, immunomodulatory and antiproliferative agents | 4SC�ɷݹ�˾ | 2004-09-01 | — | — | CN | disclosed |
| EP-1392642-A2 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2003006425-A9 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| US-20030203951-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
| WO-2003006425-A2 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203951-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | DHODH, DLD, GCDH | HCAR2 150/4885DHODH 1/4885PYGM 3339/4885 |
| US-20060199856-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | DHODH, DLD, HADHA | HCAR2 158/4885DHODH 1/4885PYGM 2989/4885 |
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | DHODH, DBH, DOHH | HCAR2 79/4885DHODH 1/4885PYGM 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.