SCHEMBL3682253

SCHEMBL3682253

C[Si](C)(C)O[Si](CCCC=CNC(=O)O)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29648092 0.87
SCHEMBL29596016 0.83
SCHEMBL3689148 0.81 SOAT2 (0.30)
SCHEMBL28461760 0.78
SCHEMBL3761063 0.75
SCHEMBL9067321 0.73 MAPT (0.34)
Bicarbonate SCHEMBL29131691 0.73 MAPT (0.38)
SCHEMBL8216450 0.72 TERT (0.39)
SCHEMBL8213814 0.72 TERT (0.39)
SCHEMBL1402612 0.72 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
CN-117924612-A Corneal contact lens and silicone contact lens 望隼科技股份有限公司 2024-04-26 CN claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
EP-3802080-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-19 EP claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
CN-113480736-A Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof 爱尔康公司 2021-10-08 CN claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
EP-3598181-B1 VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME ALCON INC (CH) 2021-06-23 EP claimed
EP-2625217-B1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS NOVARTIS AG (CH) 2018-07-04 EP claimed
EP-3113937-B1 IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2018-02-28 EP claimed
US-7584630-B2 Photochromic ocular devices TRANSITIONS OPTICAL, INC. (US) 2009-09-08 US claimed
EP-1604231-B9 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2009-01-07 EP claimed
EP-1604231-B1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2008-07-02 EP claimed
JP-2007524857-A 2007-08-30 JP claimed
US-20070113587-A1 Photochromic ocular devices TRANSITIONS OPTICAL LIMITED (IE) 2007-05-24 US claimed
EP-1604231-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL, INC. (US) 2005-12-14 EP claimed
WO-2004086103-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC. (US) 2004-10-07 WO claimed
US-20040186241-A1 Photochromic ocular devices TRANSITIONS OPTICAL, INC. 2004-09-23 US claimed
EP-0757033-B1 Vinyl carbonate and vinyl carbamate monomers for a contact lens material BAUSCH & LOMB (US) 1999-03-03 EP claimed
EP-0396364-B1 Copolymers of vinyl carbonate and vinyl carbamate as contact lens material BAUSCH & LOMB (US) 1997-06-11 EP claimed