SCHEMBL3689148

SCHEMBL3689148

C[Si](C)(C)O[Si](CCCC=CCNC(=O)O)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29683125 0.83
SCHEMBL3682253 0.81
SCHEMBL1402612 0.75 KDM4E (0.32)
SCHEMBL3761063 0.75
SCHEMBL9067321 0.73 MAPT (0.34) SOAT1
SCHEMBL4431793 0.73 MEN1 (0.31) SOAT1
Bicarbonate SCHEMBL29131691 0.73 MAPT (0.38)
SCHEMBL4023678 0.72 PPARG (0.55)
SCHEMBL4023681 0.72 PPARG (0.55)
SCHEMBL509080 0.71 CNR1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
EP-3969268-B1 METHOD FOR PRODUCING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2023-07-05 EP claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
CN-113480736-A Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof 爱尔康公司 2021-10-08 CN claimed
EP-3598181-B1 VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME ALCON INC (CH) 2021-06-23 EP claimed
EP-2625217-B1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS NOVARTIS AG (CH) 2018-07-04 EP claimed
EP-3113937-B1 IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2018-02-28 EP claimed
EP-2513711-B1 METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS NOVARTIS AG (CH) 2017-07-12 EP claimed
EP-2443486-B1 BIOMEDICAL DEVICES BAUSCH & LOMB (US) 2017-03-01 EP claimed
EP-1809344-B2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2016-08-10 EP claimed
EP-2432808-B1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2015-10-21 EP claimed
EP-2648896-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2014-09-17 EP claimed
EP-1809344-B1 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2010-01-20 EP claimed
CN-113613998-B Packaging solution for contact lenses 鲍希与洛姆伯股份有限公司 2023-04-11 CN disclosed
CN-115698776-A Insert material with high oxygen permeability coefficient and high refractive index 爱尔康公司 2023-02-03 CN disclosed
WO-2022270486-A1 CONTACT LENS AND PRODUCTION METHOD FOR SAID LENS 日油株式会社 2022-12-29 WO disclosed
US-20150153588-A1 CONTACT LENS WITH SPATIALLY HETEROGENOUS SURFACE PATTERNS FOR IMPROVED LUBRICITY UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2015-06-04 US disclosed
WO-2014012016-A1 CONTACT LENS WITH SPATIALLY HETEROGENEOUS SURFACE PATTERNS FOR IMPROVED LUBRICITY UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-01-16 WO disclosed
US-20080002146-A1 BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS BAUSCH & LOMB INCORPORATED 2008-01-03 US disclosed
CN-1299387-A Plasma surface treatment of silicone hydrogel contact lenses BAUSCH & LUMB INC (US) 2001-06-13 CN disclosed