Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509080 | 0.80 | CNR1 (0.30) | — | |
| SCHEMBL4431793 | 0.79 | MEN1 (0.31) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| Bicarbonate SCHEMBL29131691 | 0.75 | MAPT (0.38) | MAPTALDH1A1CYP3A4 | |
| SCHEMBL2121970 | 0.75 | ALDH1A1 (0.31) | MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3761063 | 0.75 | — | — | |
| Acrylamide SCHEMBL29899651 | 0.74 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL3689148 | 0.73 | SOAT2 (0.30) | SOAT1 | |
| SCHEMBL8386296 | 0.72 | MAPT (0.47) | MAPTALDH1A1MEN1FAAHTP53 | |
| SCHEMBL8386298 | 0.72 | MAPT (0.47) | MAPTALDH1A1MEN1FAAHTP53 | |
| SCHEMBL4398104 | 0.72 | ALDH1A1 (0.42) | MAPTALDH1A1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559809-B1 | SURFACE MODIFICATION OF POLYMER OBJECTS | BAUSCH & LOMB (US) | 1996-11-06 | — | — | EP | disclosed |
| US-5525691-A | Surface modification of polymeric objects | BAUSCH & LOMB INCORPORATED (US) | 1996-06-11 | — | — | US | disclosed |
| US-5364918-A | Surface modification of polymer objects | BAUSCH & LOMB INCORPORATED (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0559809-A1 | SURFACE MODIFICATION OF POLYMER OBJECTS. | BAUSCH & LOMB (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5219965-A | Adding polymerizable surfactant to monomer mixture; contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1993-06-15 | — | — | US | disclosed |
| US-5177165-A | Contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1993-01-05 | — | — | US | disclosed |
| WO-1992009644-A1 | SURFACE MODIFICATION OF POLYMER OBJECTS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |