⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509080 | 0.85 | CNR1 (0.30) | — | |
| SCHEMBL507825 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL3689148 | 0.75 | SOAT2 (0.30) | — | |
| SCHEMBL9067321 | 0.75 | MAPT (0.34) | — | |
| SCHEMBL28462971 | 0.74 | — | — | |
| Bicarbonate SCHEMBL29131691 | 0.74 | MAPT (0.38) | — | |
| SCHEMBL29112722 | 0.73 | HCAR2 (0.32) | — | |
| SCHEMBL6972270 | 0.72 | F7 (0.48) | — | |
| SCHEMBL809437 | 0.71 | TBXAS1 (0.33) | — | |
| SCHEMBL400292 | 0.71 | TBXAS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3598181-B1 | VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME | ALCON INC (CH) | 2021-06-23 | — | — | EP | claimed |
| EP-2513711-B1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2017-07-12 | — | — | EP | claimed |
| EP-3570093-B1 | CONTACT LENS WITH A HYDROPHILIC LAYER | TANGIBLE SCIENCE INC (US) | 2021-09-15 | — | — | EP | disclosed |
| CN-112352170-A | Water extractable ophthalmic device | 鲍希与洛姆伯股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-111919141-A | Silicone hydrogel contact lenses | 爱尔康公司 | 2020-11-10 | — | — | CN | disclosed |
| US-20150153588-A1 | CONTACT LENS WITH SPATIALLY HETEROGENOUS SURFACE PATTERNS FOR IMPROVED LUBRICITY | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-06-04 | — | — | US | disclosed |
| US-8999323-B2 | Composition that can be cured by polymerisation for the production of biodegradable, biocompatible, cross-linkable polymers on the basis of polyvinyl alcohol | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2015-04-07 | — | — | US | disclosed |
| US-20150057389-A1 | HYDROGEL AND SILICONE HYDROGEL DEVICES INCLUDING POLYMERIZED SURFACTANTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20100303804-A1 | COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL | TECHNISCHE UNIVERSITAT WIEN (AT) | 2010-12-02 | — | — | US | disclosed |
| US-7584630-B2 | Photochromic ocular devices | TRANSITIONS OPTICAL, INC. (US) | 2009-09-08 | — | — | US | disclosed |
| EP-1604231-B9 | PHOTOCHROMIC OCULAR DEVICES | TRANSITIONS OPTICAL INC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| US-20070113587-A1 | Photochromic ocular devices | TRANSITIONS OPTICAL LIMITED (IE) | 2007-05-24 | — | — | US | disclosed |
| US-20060292202-A1 | Drug delivery device | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | disclosed |
| WO-2006042336-A2 | REMOVAL OF IMPURITIES WITH SUPERCRITICAL FLUIDS FROM OCULAR DRUG DELIVERY DEVICES DURING MANUFACTURING | BAUSCH & LOMB INCORPORATED (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060078592-A1 | Drug delivery systems | BAUSCH & LOMB INCORPORATED | 2006-04-13 | — | — | US | disclosed |
| EP-1604231-A1 | PHOTOCHROMIC OCULAR DEVICES | TRANSITIONS OPTICAL, INC. (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | disclosed |
| WO-2004086103-A1 | PHOTOCHROMIC OCULAR DEVICES | TRANSITIONS OPTICAL INC. (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040186241-A1 | Photochromic ocular devices | TRANSITIONS OPTICAL, INC. | 2004-09-23 | — | — | US | disclosed |