Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676317 | 0.84 | ACP3 (0.41) | ACP3CNR2PPARGP2RX7LMNA | |
| SCHEMBL6680423 | 0.84 | ACP3 (0.41) | ACP3CNR2PPARGP2RX7LMNA | |
| SCHEMBL6676308 | 0.84 | ACP3 (0.41) | ACP3CNR2PPARGP2RX7LMNA | |
| SCHEMBL28821897 | 0.83 | ACP3 (0.53) | ACP3CNR2PPARGSRCLMNA | |
| SCHEMBL5452247 | 0.82 | IDO1 (0.49) | ACP3CNR2PPARGP2RX7SRC | |
| SCHEMBL8587546 | 0.80 | CTSS (0.38) | ACP3CNR2PPARGP2RX7IDO1 | |
| SCHEMBL20954016 | 0.75 | CA2 (0.41) | SRCALDH1A1 | |
| SCHEMBL4982673 | 0.74 | P2RX7 (0.47) | ACP3CNR2P2RX7LMNAIDO1 | |
| SCHEMBL7682991 | 0.74 | ACP3 (0.47) | ACP3CNR2PPARGSRCLMNA | |
| SCHEMBL13453951 | 0.73 | P2RX7 (0.50) | ACP3P2RX7LMNAIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056820-A1 | Method for the production of substituted 2-aryl malonic acid esters | BASF SE (DE) | 2010-03-04 | — | — | US | disclosed |
| EP-1077208-A3 | Process for the preparation of (bis-(trifluormethyl)-phenyl)-acetic acids and their alkyl esters as well as dialkyl esters of (bis-(trifluormethyl)-phenyl)-malonic acid | BAYER AG (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6395921-B1 | DEPROTINATION, COPPER SALT AND DILUENTS, HYDROLYSIS AND DECARBOXYLATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-28 | — | — | US | disclosed |
| US-6395921-B1 | DEPROTINATION, COPPER SALT AND DILUENTS, HYDROLYSIS AND DECARBOXYLATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-28 | — | — | US | disclosed |
| US-6395921-B1 | DEPROTINATION, COPPER SALT AND DILUENTS, HYDROLYSIS AND DECARBOXYLATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-28 | — | — | US | disclosed |
| JP-2001081065-A | METHOD FOR PRODUCING [BIS-(TRIFLUOROMETHYL)-PHENYL]- ACETIC ACID, ITS ALKYL ESTER AND DIALKYL BIS-(TRIFLUOROMETHYL)-PHENYL]-MALONATE | BAYER AG | 2001-03-27 | — | — | JP | disclosed |
| EP-1077208-A2 | Process for the preparation of (bis-(trifluormethyl)-phenyl)-acetic acids and their alkyl esters as well as dialkyl esters of (bis-(trifluormethyl)-phenyl)-malonic acid | BAYER AG (DE) | 2001-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056820-A1 | Method for the production of substituted 2-aryl malonic acid esters | ME1, AKR1C3, AKR1C4 | ACP3 2398/4885CNR2 857/4885PPARG 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.