SCHEMBL36825

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3679228	0.82	ALDH1A1 (0.35)	NPSR1POLBDRD2CA12CA1
	SCHEMBL36153	0.81	TRPA1 (0.42)	TRPA1DRD2CA12CA1CA9
	SCHEMBL38658450	0.80	NPSR1 (0.37)	NPSR1POLBTRPA1DRD2MAPT
	SCHEMBL36605	0.78	CA12 (0.38)	CA12CA1CA9
	SCHEMBL25365134	0.77	TRPA1 (0.50)	TRPA1DRD2MAPTATM
	SCHEMBL30540735	0.77	TRPA1 (0.50)	TRPA1DRD2MAPTATM
	SCHEMBL7332445	0.76	PPARA (0.32)	NPSR1POLB
	SCHEMBL16418139	0.73	ALDH1A1 (0.37)	NPSR1POLBDRD2MAPT
	SCHEMBL30540736	0.73	DRD2 (0.42)	TRPA1DRD2
	SCHEMBL25366327	0.73	DRD2 (0.40)	TRPA1DRD2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.