Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.70 |
| ▸ | CCNE2 | O96020 | 12/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.51 |
| ▸ | CDK2 | P24941 | 12/20 | 0.51 |
| ▸ | PDE5A | O76074 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | PDE6C | P51160 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686041 | 0.83 | CCNE2 (0.77) | CCNE2CCNE1CDK2PDE5APDE4D | |
| SCHEMBL3682525 | 0.79 | PRUNE1 (0.67) | PRUNE1CCNE2CCNE1CDK2PDE5A | |
| SCHEMBL7971734 | 0.79 | PRUNE1 (0.60) | PRUNE1CCNE2CCNE1CDK2PDE5A | |
| SCHEMBL7960337 | 0.75 | PRUNE1 (0.59) | PRUNE1CCNE2CCNE1CDK2PDE5A | |
| SCHEMBL27221084 | 0.74 | CCNE2 (0.71) | PRUNE1CCNE2CCNE1CDK2CDK1 | |
| SCHEMBL15619030 | 0.72 | CCNE2 (0.68) | PRUNE1CCNE2CCNE1CDK2PDE5A | |
| SCHEMBL5827486 | 0.71 | CDK2 (0.58) | CCNE2CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL15618715 | 0.68 | CDK2 (0.71) | PRUNE1CCNE2CCNE1CDK2CCNT1 | |
| SCHEMBL3106797 | 0.67 | APP (0.61) | PRUNE1PDE5APDE4DPDE6C | |
| SCHEMBL11747999 | 0.67 | PTGES (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056710-A1 | COMPOSITIONS AND METHODS FOR TREATING EYE DISEASES | BIOVISTA, INC. (US) | 2010-05-20 | — | — | WO | disclosed |