Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 10/20 | 0.77 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.77 |
| ▸ | CDK2 | P24941 | 10/20 | 0.77 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.77 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.77 |
| ▸ | CDK1 | P06493 | 4/20 | 0.77 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.77 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.77 |
| ▸ | PDE5A | O76074 | 1/20 | 0.77 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.77 |
| ▸ | CDK7 | P50613 | 1/20 | 0.77 |
| ▸ | CDK9 | P50750 | 1/20 | 0.77 |
| ▸ | CCNH | P51946 | 1/20 | 0.77 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.77 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.77 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394958 | 0.87 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL4272902 | 0.86 | CCNE2 (0.84) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL1394954 | 0.85 | CCNE1 (0.77) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL3682526 | 0.83 | PRUNE1 (0.70) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| Myoseverin SCHEMBL13325947 | 0.81 | TDP1 (1.00) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| Myoseverin SCHEMBL29376276 | 0.81 | TDP1 (1.00) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL5466712 | 0.80 | CCNE1 (0.70) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL1443236 | 0.79 | TDP1 (0.80) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL13359693 | 0.79 | TDP1 (0.90) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL14587794 | 0.77 | TDP1 (0.78) | CCNE2CCNE1CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764118-B1 | Polymer coating for medical devices | GILEAD PALO ALTO INC (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-1937328-B1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS INC (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7419709-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20080160166-A1 | POLYMER COATING FOR MEDICAL DEVICES | RYPACEK FRANTISEK | 2008-07-03 | — | — | US | disclosed |
| EP-1937328-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2008-07-02 | — | — | EP | disclosed |
| US-7364768-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2008-04-29 | — | — | US | disclosed |
| WO-2007041972-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20070071926-A1 | Polymer coating for medical devices | RYPACEK FRANTISEK | 2007-03-29 | — | — | US | disclosed |
| US-20070071879-A1 | Polymer coating for medical devices | RYPACEK FRANTISEK | 2007-03-29 | — | — | US | disclosed |
| EP-1764118-A2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-1492581-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6794390-B2 | TREATING CELL PROLIFERATIVE DISORDERS SUCH AS RHEUMATOID ARTHRITIS, LUPUS, TYPE I DIABETES, MULTIPLE SCLEROSIS, CANCER, RESTENOSIS, HOST GRAFT DISEASE, GOUT, AND POLYCYSTIC KIDNEY DISEASE. | CV THERAPEUTICS, INC. | 2004-09-21 | — | — | US | disclosed |
| US-6790958-B2 | ANTIPROLIFERATIVE AGENTS; FUNGICIDES | LUM ROBERT T (US) | 2004-09-14 | — | — | US | disclosed |
| US-20030219562-A1 | Polymer coating for medical devices | CV THERAPEUTICS, INC. | 2003-11-27 | — | — | US | disclosed |
| WO-2003068289-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2003-08-21 | — | — | WO | disclosed |
| US-20020035252-A1 | Purine inhibitors of cyclin dependent kinase 2 & IkBa | LUM ROBERT T (US) | 2002-03-21 | — | — | US | disclosed |
| US-20020032327-A1 | Purine inhibitors of cyclin dependent kinase 2 & IkappaBalpha | CV THERAPEUTICS, INC. | 2002-03-14 | — | — | US | disclosed |
| EP-1150982-A1 | PURINE INHIBITORS OF CYCLIN DEPENDENT KINASE 2 AND I$g(k)-A$g(a) | CV THERAPEUTICS, INC. (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000044750-A1 | PURINE INHIBITORS OF CYCLIN DEPENDENT KINASE 2 AND Iλ-A$g(a) | CV THERAPEUTICS, INC. (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-1998005335-A9 | PURINE INHIBITORS OF CYCLIN DEPENDENT KINASE 2 AND IλB-$g(a) | — | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032327-A1 | Purine inhibitors of cyclin dependent kinase 2 & IkappaBalpha | CDKN1A, CCNK, CDK1 | CCNE2 132/4885CCNE1 82/4885CDK2 4/4885 |
| US-20020035252-A1 | Purine inhibitors of cyclin dependent kinase 2 & IkBa | AURKB, CDKN1A, IKBKB | CCNE2 202/4885CCNE1 96/4885CDK2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.