SCHEMBL3683453

SCHEMBL3683453

O=C(Cl)C1C2CC3CC(C2)CC1(C(=O)Cl)C3

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.34
EPHX1 P07099 1/20 0.34
HTT P42858 2/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 3/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
GLA P06280 1/20 0.32
THRB P10828 1/20 0.31
CYP2C9 P11712 1/20 0.31
GAA P10253 2/20 0.31
TSHR P16473 1/20 0.31
HSD11B1 P28845 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
JAK2 O60674 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030898 0.75 EPHX2 (0.34) EPHX2EPHX1LMNAALDH1A1THRB
SCHEMBL927164 0.73 P2RX7 (0.42) EPHX2EPHX1LMNAALDH1A1THRB
SCHEMBL26217909 0.71 THRB (0.35) EPHX2EPHX1HTTALDH1A1THRB
SCHEMBL74823 0.71 THRB (0.35) EPHX2EPHX1HTTALDH1A1THRB
SCHEMBL1578432 0.69 ALDH1A1 (0.37) EPHX2EPHX1HTTLMNAALDH1A1
SCHEMBL6859431 0.69 EPHX2 (0.33) EPHX2EPHX1ALDH1A1THRBCYP2C9
Hydrochloric Acid SCHEMBL3683456 0.69 THRB (0.34) EPHX2EPHX1LMNAALDH1A1THRB
SCHEMBL7587941 0.67 HSD11B1 (0.35) HTTLMNAALDH1A1CRHBPCRHR2
SCHEMBL905306 0.67 THRB (0.39) EPHX2EPHX1HTTLMNAALDH1A1
SCHEMBL27750790 0.67 THRB (0.35) EPHX2EPHX1HTTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3363845-B1 POLYAMIDE-IMIDE LG CHEMICAL LTD (KR) 2023-08-30 EP disclosed
EP-3736305-B1 POLYAMIDE-IMIDE, METHOD FOR PREPARING SAME, AND POLYAMIDE-IMIDE FILM USING SAME LG CHEMICAL LTD (KR) 2022-01-05 EP disclosed
EP-3450482-B1 HIGH-STRENGTH TRANSPARENT POLYAMIDE-IMIDE AND METHOD FOR MANUFACTURING SAME LG CHEMICAL LTD (KR) 2021-03-03 EP disclosed
EP-3736305-A1 POLYAMIDE-IMIDE, METHOD FOR PREPARING SAME, AND POLYAMIDE-IMIDE FILM USING SAME LG CHEM, LTD. (KR) 2020-11-11 EP disclosed
CN-108431090-B High-strength transparent polyamide-imide and method for producing same 株式会社LG化学 2020-08-28 CN disclosed
EP-3366726-B1 HIGH-STRENGTH TRANSPARENT POLYAMIDIMIDE AND METHOD FOR PREPARING SAME LG CHEMICAL LTD (KR) 2019-07-03 EP disclosed
US-20190023846-A1 HIGH STRENGTH TRANSPARENT POLYAMIDE-IMIDE AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2019-01-24 US disclosed
US-20190016849-A1 POLYAMIDE-IMIDE, METHOD FOR PREPARING SAME, AND POLYAMIDE-IMIDE FILM USING SAME LG CHEM, LTD. (KR) 2019-01-17 US disclosed
US-20190010292-A1 HIGH-STRENGTH TRANSPARENT POLYAMIDE-IMIDE AND METHOD FOR MANUFACTURING SAME LG CHEM, LTD. (KR) 2019-01-10 US disclosed
EP-3366726-A1 HIGH-STRENGTH TRANSPARENT POLYAMIDIMIDE AND METHOD FOR PREPARING SAME LG Chem, Ltd. (KR) 2018-08-29 EP disclosed
US-6824957-B2 RESIST COMPOSITION HAVING HIGH TRANSPARENCY AGAINST SHORT-WAVELENGTH LIGHT AND HIGH DRY- ETCHING RESISTANCE, CAPABLE OF FORMING A RESIST PATTERN EXCELLENT IN ADHESION AND RESOLUTION BY MEANS OF ALKALI DEVELOPMENT KABUSHIKI KAISHA TOSHIBA (JP) 2004-11-30 US disclosed
US-6794528-B2 HEAT RESISTANCE, FLAME RETARDERS, STABILIZERS; REACTING DIALCOHOL COMPOUND WITH A PHOSPHYL OXYCHLORIDE COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-21 US disclosed
US-20040043324-A1 Resin useful for resist, resist composition and pattern forming process using the same KABUSHIKI KAISHA TOSHIBA (JP) 2004-03-04 US disclosed
US-6660450-B2 Acrylic ester polymer having pendant adamantane rings with oxygenated substitution; ultraviolet light transparency; dry etching resistance KABUSHIKI KAISHA TOSHIBA (JP) 2003-12-09 US disclosed
US-20030149225-A1 Resin useful for resist, resist composition and pattern forming process using the same KABUSHIKI KAISHA TOSHIBA (JP) 2003-08-07 US disclosed
US-20030109736-A1 Phosphorus compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-12 US disclosed
US-6541597-B2 Resist resin having in its structure a bridged bond containing aliphatic ring; pattern excellent in transparency against short wavelength light and dry-etching resistance can be formed by alkali development with high resolution. KABUSHIKI KAISHA TOSHIBA (JP) 2003-04-01 US disclosed
EP-1277758-A1 PHOSPHORUS COMPOUND Daicel Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed
US-20020098441-A1 Resin useful for resist, resist composition and pattern forming process using the same KABUSHIKI KAISHA TOSHIBA (JP) 2002-07-25 US disclosed
US-6303266-B1 FOR PATTERN HAVING TRANSPARENCY AGAINST SHORT-WAVELENGTH LIGHT AND DRY-ETCHING RESISTANCE CAN BE FORMED BY ALKALI DEVELOPMENT WITH HIGH RESOLUTION KABUSHIKI KAISHA TOSHIBA (JP) 2001-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109736-A1 Phosphorus compound NR4A1, POLL, NR0B1 EPHX2 3620/4885EPHX1 3912/4885HTT 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.