Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.32 |
| ▸ | GRM6 | O15303 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243807 | 0.83 | ALDH1A1 (0.38) | THRBCYP2C9EPHX1EPHX2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29663474 | 0.78 | GRM4 (0.34) | CYP2C9ALDH1A1ALOX15GRM5GRM2 | |
| SCHEMBL11344046 | 0.77 | ALDH1A1 (0.42) | EPHX1EPHX2ALDH1A1TSHRNPC1 | |
| SCHEMBL59961 | 0.77 | CYP2C9 (0.36) | THRBCYP2C9EPHX1EPHX2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11330580 | 0.76 | ALDH1A1 (0.41) | EPHX1EPHX2ALDH1A1TSHRNPC1 | |
| SCHEMBL26963220 | 0.76 | CYP2C9 (0.39) | THRBCYP2C9EPHX1EPHX2ALDH1A1 | |
| Bicarbonate SCHEMBL905261 | 0.75 | THRB (0.39) | THRBCYP2C9EPHX1EPHX2ALDH1A1 | |
| SCHEMBL1072000 | 0.75 | THRB (0.35) | THRBCYP2C9EPHX1EPHX2ALDH1A1 | |
| SCHEMBL74823 | 0.75 | THRB (0.35) | THRBCYP2C9EPHX1EPHX2ALDH1A1 | |
| SCHEMBL1088728 | 0.75 | THRB (0.35) | THRBCYP2C9EPHX1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361280-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | claimed |
| EP-4472995-A2 | CONJUGATED HEPCIDIN MIMETICS | Protagonist Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | claimed |
| WO-2023150618-A2 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | claimed |
| EP-2272825-B1 | Protected amino hydroxy adamantane carboxylic acid and process for its preparation | ASTRAZENECA AB (SE) | 2015-11-04 | — | — | EP | claimed |
| WO-2013111158-A2 | PROCESS FOR THE PREPARATION OF DPP-IV INHIBITOR | MSN LABORATORIES LIMITED (IN) | 2013-08-01 | — | — | WO | claimed |
| EP-2272825-A2 | N-Protected amino hydroxy adamantane carboxylic acid and process for its preparation | Bristol-Myers Squibb Company (US) | 2011-01-12 | — | — | EP | claimed |
| CN-101747221-A | Method for preparing amino adamantane carboxylic acid compounds | UNIV GUANGDONG TECHNOLOGY | 2010-06-23 | — | — | CN | claimed |
| EP-1559710-A2 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV, process for their preparation and their use | Bristol-Myers Squibb Company (US) | 2005-08-03 | — | — | EP | claimed |
| US-20260078095-A1 | NEUROTENSIN RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2026-03-19 | — | — | US | disclosed |
| US-20250361280-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | disclosed |
| EP-4472995-A2 | CONJUGATED HEPCIDIN MIMETICS | Protagonist Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023150618-A2 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| EP-3712131-B1 | NEUROTENSIN RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2023-02-01 | — | — | EP | disclosed |
| CN-109320502-B | Neurotensin receptor ligands | 3B制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-101747221-A | Method for preparing amino adamantane carboxylic acid compounds | UNIV GUANGDONG TECHNOLOGY | 2010-06-23 | — | — | CN | disclosed |
| CN-101747221-A | Method for preparing amino adamantane carboxylic acid compounds | UNIV GUANGDONG TECHNOLOGY | 2010-06-23 | — | — | CN | disclosed |
| US-20080275112-A1 | Invention Concerning Aminoadamantane Compounds | SCHREINER PETER R | 2008-11-06 | — | — | US | disclosed |
| EP-1751108-A1 | ADAMANTYL-ACETAMIDE DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | ABBOTT LABORATORIES (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005108368-A1 | ADAMANTYL-ACETAMIDE DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | ABBOTT LABORATORIES (US) | 2005-11-17 | — | — | WO | disclosed |
| US-4273704-A | N-Adamantane-substituted tetrapeptide amides | G. D. SEARLE & CO. (US) | 1981-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361280-A1 | CONJUGATED HEPCIDIN MIMETICS | HAMP, VIP, HDGF | THRB 910/4885CYP2C9 2209/4885EPHX1 2087/4885 |
| US-20080275112-A1 | Invention Concerning Aminoadamantane Compounds | GABRA5, GABRA1, GABRA4 | THRB 2133/4885CYP2C9 2030/4885EPHX1 1850/4885 |
| US-20260078095-A1 | NEUROTENSIN RECEPTOR LIGANDS | NTSR1, NTSR2, GRPR | THRB 364/4885CYP2C9 4294/4885EPHX1 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.