SCHEMBL3683576

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL719061	0.86	CISD2 (0.47)	LMNATP53MAPTKMT2AMEN1
	SCHEMBL20893397	0.82	ALDH1A1 (0.52)	LMNATP53MAPTKMT2AMEN1
	SCHEMBL2895391	0.82	GPR35 (0.54)	LMNAKMT2AMEN1KDM4EALDH1A1
	SCHEMBL14691616	0.81	CA12 (0.53)	LMNAMAPTKMT2AMEN1KDM4E
	SCHEMBL6659125	0.80	MAPT (0.49)	LMNAMAPTKMT2AMEN1KDM4E
	SCHEMBL3488612	0.80	ALDH1A1 (0.51)	LMNATP53MAPTKMT2AMEN1
	SCHEMBL10947088	0.80	KMT2A (0.50)	LMNATP53MAPTKMT2AMEN1
	SCHEMBL14691163	0.80	MAPT (0.58)	LMNATP53MAPTKMT2AMEN1
	SCHEMBL4655051	0.80	SMN1; SMN2 (0.39)	LMNATP53MAPTKMT2AMEN1
	SCHEMBL30099150	0.80	LMNA (0.48)	LMNATP53MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.