Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529272 | 1.00 | THRA (0.36) | THRATHRBNR1H2CNR1CNR2 | |
| SCHEMBL28524387 | 0.85 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL7550865 | 0.84 | GABRA5 (0.39) | EPHX1 | |
| SCHEMBL28644405 | 0.82 | THRA (0.34) | THRATHRBCNR2EPHX1 | |
| SCHEMBL28529221 | 0.80 | HSD11B1 (0.36) | THRATHRB | |
| SCHEMBL5969001 | 0.78 | NOS2 (0.41) | THRATHRB | |
| SCHEMBL28586161 | 0.77 | CPB1 (0.34) | THRATHRB | |
| SCHEMBL28594264 | 0.77 | CPB1 (0.34) | THRATHRB | |
| SCHEMBL28603572 | 0.77 | CPB1 (0.34) | THRATHRB | |
| SCHEMBL28608372 | 0.77 | CPB1 (0.34) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |