Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445984 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL27792400 | 0.79 | CTH (0.34) | CA2EGLN1CHIT1 | |
| Trifluoroacetic Acid SCHEMBL28336879 | 0.78 | CA2 (0.47) | CA2CA1KDM4ECHIT1 | |
| Trifluoroacetic Acid SCHEMBL2587874 | 0.76 | MCL1 (0.34) | CA2CA1HDAC1HDAC6HDAC4 | |
| Trifluoroacetic Acid SCHEMBL4276694 | 0.76 | CHIT1 (0.35) | CHIT1 | |
| Trifluoroacetic Acid SCHEMBL11688514 | 0.73 | CA2 (0.40) | MMP1CA2CA1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL2435717 | 0.72 | CA2 (0.40) | CA2CHIT1 | |
| Trifluoroacetic Acid SCHEMBL3955601 | 0.72 | CACNA1B (0.33) | HDAC4 | |
| Trifluoroacetic Acid SCHEMBL4846623 | 0.72 | CACNA1B (0.33) | HDAC4 | |
| Trifluoroacetic Acid SCHEMBL504173 | 0.71 | FOLH1 (0.73) | MMP1CA2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662856-B2 | Compositions having antimycrobial activity including a hydroxamate or a hydroxamate and a hydroxlyamine | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2010-02-16 | — | — | US | disclosed |
| US-20080249181-A1 | Compositions Having Antimycrobial Activity Including a Hydroxamate or a Hydroxamate and a Hydroxlyamine | KOHN HAROLD | 2008-10-09 | — | — | US | disclosed |
| WO-2005020973-A2 | COMPOSITIONS HAVING ANTIMYCROBIAL ACTIVITY INCLUDING A HYDROXAMATE OR A HYDROXAMATE AND A HYDROXYLAMINE | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2005-03-10 | — | — | WO | disclosed |
| EP-0337348-B1 | Amides of cyclomethylen-1,2-bicarboxylic acids having therapeutical activity, processes for their preparation and pharmaceutical compositions containing them | GUIDOTTI & C SPA LABOR (IT) | 1994-02-02 | — | — | EP | disclosed |
| US-5095137-A | Hypotensives | LABORATORI GUIDOTTI SPA (IT) | 1992-03-10 | — | — | US | disclosed |
| EP-0337348-A2 | Amides of cyclomethylen-1,2-bicarboxylic acids having therapeutical activity, processes for their preparation and pharmaceutical compositions containing them | Laboratori Guidotti S.p.A. (IT) | 1989-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249181-A1 | Compositions Having Antimycrobial Activity Including a Hydroxamate or a Hydroxamate and a Hydroxlyamine | CD68, HAAO, HOGA1 | MMP1 61/4885CA2 488/4885CA1 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.