SCHEMBL476498

SCHEMBL476498

C=CC(=O)NC(C)OCCO

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ACACB O00763 2/20 0.35
CYP2C19 P33261 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11159463 0.89 TSHR (0.52) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL5685783 0.81 TSHR (0.48) TSHRALDH1A1MAPK1ACACBZDHHC20
SCHEMBL368428 0.80 TSHR (0.56) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL7096451 0.79 ALDH1A1 (0.34) ALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL4297710 0.79 TSHR (0.67) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL9293036 0.78 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL10324563 0.78 CYP2D6 (0.33) ALDH1A1CYP2C19
SCHEMBL25256479 0.76 CAD (0.33) ALDH1A1
SCHEMBL8615608 0.76 TGFBR1 (0.46) TSHRALDH1A1
Ethylene Glycol SCHEMBL12472882 0.75 TSHR (0.82) TSHRALDH1A1MAPK1TDP1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 451 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456250-B1 POLY(VINYLALCOHOL),CO-POLY(VINYLAMINE) POLYMERS COMPRISING FUNCTIOAL MOIETIES CIBA HOLDING INC (CH) 2009-01-14 EP claimed
US-20050020729-A1 Poly(vinylalcohol)-co-poly(vinylamine)polymers comprising functional moieties CIBA SPECIALTY CHEMICALS CORP. 2005-01-27 US claimed
EP-1456250-A2 POLY(VINYLALCOHOL),CO-POLY(VINYLAMINE) POLYMERS COMPRISING FUNCTIOAL MOIETIES Ciba SC Holding AG (CH) 2004-09-15 EP claimed
WO-2003054030-A2 POLY(VINYLALCOHOL)-CO-POLY(VINYLAMINE) POLYMERS COMPRISING FUNCTIOAL MOIETIES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-07-03 WO claimed
US-5470916-A Formulations for polyacrylamide matrices in electrokinetic and chromatographic methodologies RIGHETTI PIER G (IT) 1995-11-28 US claimed
EP-0538683-A1 Polyamic acid and polyimide from fluorinated reactant International Business Machines Corporation (US) 1993-04-28 EP claimed
US-5100767-A Epoxy resins TAMURA KAKEN CO., LTD. (JP) 1992-03-31 US claimed
EP-3631432-B1 COMPOSITIONS, METHODS FOR MOLECULAR ANALYSIS INTEGENX INC (US) 2026-01-14 EP disclosed
US-20250189485-A1 COMPOSITIONS, METHODS, KITS AND DEVICES FOR MOLECULAR ANALYSIS Life Technologies Corporation (US) 2025-06-12 US disclosed
US-12153014-B2 Compositions, methods, kits and devices for molecular analysis IntegenX, Inc. (US) 2024-11-26 US disclosed
CN-118201906-A Novel photoinitiators 意大利艾坚蒙树脂有限公司 2024-06-14 CN disclosed
CN-112673012-B Multifunctional bisacylphosphine oxide photoinitiator 意大利艾坚蒙树脂有限公司 2024-05-24 CN disclosed
US-11981650-B2 Coumarin glyoxylates for LED photocuring IGM RESINS ITALIA S.R.L. (IT) 2024-05-14 US disclosed
US-4268610-A Photoresist formulations HERCULES INCORPORATED (US) 1981-05-19 US disclosed
EP-0024391-A1 CONTRAST COLORANT FOR PHOTOPOLYMERIZABLE COMPOSITIONS XIDEX CORPORATION (US) 1981-03-11 EP disclosed
US-4239849-A FLEXIBILITY, PLASTICITY DYNACHEM CORPORATION (US) 1980-12-16 US disclosed
WO-1980001846-A1 CONTRAST COLORANT FOR PHOTOPOLYMERIZABLE COMPOSITIONS XIDEX CORP (US) 1980-09-04 WO disclosed
EP-0014237-A2 Photosensitive coating composition and its use in the production of a negative resist image International Business Machines Corporation (US) 1980-08-20 EP disclosed
EP-0003040-A2 Light-sensitive coating material and process for the production of a negative photo resist image International Business Machines Corporation (US) 1979-07-25 EP disclosed
US-4065315-A Phototropic dye system and photosensitive compositions containing the same DYNACHEM CORPORATION (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981650-B2 Coumarin glyoxylates for LED photocuring AGXT, GRHPR, GLO1 TSHR 4878/4885ALDH1A1 1173/4885MAPK1 4351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.