SCHEMBL368476

SCHEMBL368476

Nc1ncnc2c1nnn2[C@H]1CC(O)[C@@H](CO)O1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 1/20 0.58
▸ ADORA3 P0DMS8 2/20 0.53
▸ ADORA2A P29274 2/20 0.53
▸ HIF1A Q16665 1/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ PNP P00491 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ PDE4D Q08499 1/20 0.48
▸ PDE3A Q14432 1/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.48
▸ DNMT1 P26358 3/20 0.45
▸ ATG7 O95352 2/20 0.45
▸ FPR2 P25090 1/20 0.45
▸ DNMT3B Q9UBC3 1/20 0.45
▸ DPP4 P27487 1/20 0.45
▸ ADRB1 P08588 1/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ SLC28A1 O00337 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3765564 1.00 AHCY (0.58) AHCYADORA3ADORA2AHIF1ASMN1; SMN2
SCHEMBL20377688 0.83 PNP (0.45) AHCYADORA3ADORA2AHIF1ASMN1; SMN2
SCHEMBL22577509 0.82 PNP (0.45) AHCYADORA3ADORA2AHIF1ASMN1; SMN2
Deoxyadenosine SCHEMBL5182039 0.80 HIF1A (0.71) ADORA3ADORA2AHIF1ASMN1; SMN2PNP
Deoxyadenosine SCHEMBL21637036 0.80 HIF1A (0.71) ADORA3ADORA2AHIF1ASMN1; SMN2PNP
Deoxyadenosine SCHEMBL23982174 0.80 HIF1A (0.71) ADORA3ADORA2AHIF1ASMN1; SMN2PNP
Deoxyadenosine SCHEMBL532825 0.80 HIF1A (0.71) ADORA3ADORA2AHIF1ASMN1; SMN2PNP
Deoxyadenosine SCHEMBL193181 0.80 HIF1A (0.71) ADORA3ADORA2AHIF1ASMN1; SMN2PNP
Deoxyadenosine SCHEMBL593935 0.80 HIF1A (0.71) ADORA3ADORA2AHIF1ASMN1; SMN2PNP
Deoxyadenosine SCHEMBL19877 0.80 HIF1A (0.71) ADORA3ADORA2AHIF1ASMN1; SMN2PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2711009-A1 Compounds for use in treating or preventing primary and metastatic breast and prostate cancer Institut Univ. de Ciència i Tecnologia, S.A. (ES) 2014-03-26 — — EP claimed
EP-2711008-A1 N6,N6-dimethyladenosine for use in treating or preventing primary and metastatic breast cancer Institut Univ. de Ciència i Tecnologia, S.A. (ES) 2014-03-26 — — EP claimed
EP-2711007-A1 4-Aminopyrazolo[3,4-d]pyrimidine for use in treating or preventing primary and metastatic breast and prostate cancer Institut Univ. de Ciència i Tecnologia, S.A. (ES) 2014-03-26 — — EP claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 — — US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 — — US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 — — US disclosed
US-20240182906-A1 GENOME EDITING USING EFFECTOR OLIGONUCLEOTIDES FOR THERAPEUTIC TREATMENT Research Foundation to Cure AIDS, Inc. (US) 2024-06-06 — — US disclosed
EP-4363613-A1 DETECTING METHYLCYTOSINE USING A MODIFIED BASE OPPOSITE TO THE METHYLCYTOSINE ILLUMINA, INC. (US) 2024-05-08 — — EP disclosed
US-20240117337-A1 METHODS AND POLYNUCLEOTIDES FOR AMPLIFYING A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-04-11 — — US disclosed
US-20240076719-A9 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-03-07 — — US disclosed
CN-117561339-A Detection of methylcytosine using modified bases opposite methylcytosine 因美纳有限公司 2024-02-13 — — CN disclosed
US-20060094869-A1 Selective process for producing an anomer of a 1-phosphorylated saccharide derivative and process for producing a nucleoside MITSUI CHEMICALS, INC. (JP) 2006-05-04 — — US disclosed
US-7038039-B2 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside MITSUI CHEMICALS, INC. (JP) 2006-05-02 — — US disclosed
EP-1641942-A2 COMBINATORIAL NUCLEOBASE OLIGOMERS COMPRISING UNIVERSAL BASE ANALOGUES AND METHODS FOR MAKING AND USING SAME Applera Corporation (US) 2006-04-05 — — EP disclosed
US-20050053979-A1 Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same APPLIED BIOSYSTEMS, LLC 2005-03-10 — — US disclosed
WO-2004111072-A2 COMBINATORIAL NUCLEOBASE OLIGOMERS COMPRISING UNIVERSAL BASE ANALOGUES AND METHODS FOR MAKING AND USING SAME APPLERA CORPORATION (US) 2004-12-23 — — WO disclosed
US-20020193314-A1 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside MITSUI CHEMICALS, INC. (JP) 2002-12-19 — — US disclosed
EP-1214331-A2 2-AZAPURINE COMPOUNDS AND THEIR USE Roche Diagnostics GmbH (DE) 2002-06-19 — — EP disclosed
EP-1178051-A2 PROCESS FOR SELECTIVELY PRODUCING 1-PHOSPHORYLATED SUGAR DERIVATIVE ANOMER AND PROCESS FOR PRODUCING NUCLEOSIDE Mitsui Chemicals, Inc. (JP) 2002-02-06 — — EP disclosed
WO-2001016149-A2 2-AZAPURINE COMPOUNDS AND THEIR USE ROCHE DIAGNOSTICS GMBH (DE) 2001-03-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM AHCY 3814/4885ADORA3 1197/4885ADORA2A 1754/4885
US-20060094869-A1 Selective process for producing an anomer of a 1-phosphorylated saccharide derivative and process for producing a nucleoside PNP, MTAP, GALE AHCY 2247/4885ADORA3 503/4885ADORA2A 486/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 AHCY 2590/4885ADORA3 1734/4885ADORA2A 2575/4885
US-20050053979-A1 Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same DTYMK, UNG, TPR AHCY 841/4885ADORA3 1671/4885ADORA2A 2400/4885
US-20020193314-A1 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside PNP, GALE, MTAP AHCY 2124/4885ADORA3 544/4885ADORA2A 464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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