Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3688240 | 0.89 | MEN1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7938880 | 0.86 | CHRNB2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3687227 | 0.84 | EDNRB (0.38) | — | |
| Hydrochloric Acid SCHEMBL3694697 | 0.83 | EDNRB (0.34) | — | |
| Hydrochloric Acid SCHEMBL3694509 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL3687089 | 0.83 | EDNRB (0.30) | — | |
| Hydrochloric Acid SCHEMBL3687770 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3690696 | 0.81 | HSD11B1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL3685190 | 0.80 | KIF11 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3689350 | 0.79 | HSD11B1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056737-A1 | Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2010-03-04 | — | — | US | disclosed |