SCHEMBL4431793

SCHEMBL4431793

C[Si](C)(C)O[Si](CCCC=CCOC(N)=O)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
FAAH O00519 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
SOAT1 P35610 1/20 0.31
KMT2A Q03164 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509080 0.79 CNR1 (0.30)
SCHEMBL9067321 0.79 MAPT (0.34) MEN1FAAHTP53CYP1A2CYP3A4
SCHEMBL8501219 0.76 CHRM2 (0.39) CYP2C19ALOX15
SCHEMBL3689148 0.73 SOAT2 (0.30) SOAT1
SCHEMBL1416181 0.73 FAAH (0.58) MEN1FAAHTP53CYP1A2CYP3A4
SCHEMBL1416177 0.73 FAAH (0.58) MEN1FAAHTP53CYP1A2CYP3A4
SCHEMBL28080510 0.72 ALOX15 (0.39) MEN1FAAHTP53CYP1A2CYP3A4
SCHEMBL3761063 0.71
SCHEMBL2121970 0.71 ALDH1A1 (0.31) CYP3A4CYP2C19
SCHEMBL1416727 0.70 ALOX15 (0.46) MEN1FAAHTP53CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111919141-A Silicone hydrogel contact lenses 爱尔康公司 2020-11-10 CN disclosed
WO-2009085642-A1 TRIMETHYLSILYL-CAPPED POLYSILOXANE MACROMONOMERS CONTAINING POLAR FLUORINATED SIDE-CHAINS BAUSCH & LOMB INCORPORATED (US) 2009-07-09 WO disclosed
US-20090168013-A1 Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains BAUSCH & LOMB INCORPORATED 2009-07-02 US disclosed
US-5321108-A Improving solubility of unsaturated siloxane monomers in hydrophilic monomer BAUSCH & LOMB INCORPORATED (US) 1994-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090168013-A1 Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains VCL, PCNA, MLEC MEN1 2050/4885FAAH 3114/4885TP53 3040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.