SCHEMBL509080

SCHEMBL509080

C[Si](C)(C)O[Si](CCCC=COC(N)=O)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3761063 0.85
SCHEMBL28493896 0.83 CNR1 (0.33) CNR1
SCHEMBL9067321 0.80 MAPT (0.34)
SCHEMBL4431793 0.79 MEN1 (0.31)
SCHEMBL28413472 0.75
SCHEMBL11570155 0.73 CNR1 (0.48) CNR1
SCHEMBL2121970 0.72 ALDH1A1 (0.31)
SCHEMBL3689148 0.71 SOAT2 (0.30)
SCHEMBL8501219 0.70 CHRM2 (0.39)
Bicarbonate SCHEMBL29131691 0.69 MAPT (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 636 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
EP-4514597-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4514596-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
WO-2011075377-A1 METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS NOVARTIS AG (CH) 2011-06-23 WO claimed
WO-2011071790-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES NOVARTIS AG (CH) 2011-06-16 WO claimed
US-20110140292-A1 METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS ALCON INC. (CH) 2011-06-16 US claimed
US-20110133350-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES ALCON INC. (CH) 2011-06-09 US claimed
WO-2010133680-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2010-11-25 WO claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed
US-20080231798-A1 Prepolymers with dangling polysiloxane-containing polymer chains ALCON INC. (CH) 2008-09-25 US claimed
US-20080143003-A1 Actinically curable silicone hydrogel copolymers and uses thereof ALCON INC. (CH) 2008-06-19 US claimed
WO-2007064594-A2 NEW COATINGS ON OPHTHALMIC LENSES BAUSCH & LOMB INCORPORATED (US) 2007-06-07 WO claimed
US-20070122540-A1 Coatings on ophthalmic lenses BAUSCH & LOMB INCORPORATED 2007-05-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES CRYZ, STRA6, PHOSPHO1 CNR1 3995/4885
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 CNR1 2379/4885
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA CNR1 3944/4885
US-12638614-B2 Method for making silicone hydrogel contact lenses SMCHD1, CRYAA, CRYZ CNR1 4076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.