Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821629 | 0.98 | TP53 (0.40) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL821547 | 0.98 | TP53 (0.40) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL822038 | 0.98 | TP53 (0.40) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL10712270 | 0.83 | KDM4E (0.44) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL1107767 | 0.76 | TP53 (0.48) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL16378246 | 0.76 | TP53 (0.48) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL231005 | 0.76 | ESR1 (0.56) | TP53KDM4ECYP3A4MAPTCALM1 | |
| SCHEMBL843022 | 0.76 | CALM1 (0.45) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL28453487 | 0.73 | TP53 (0.46) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL8517700 | 0.72 | TP53 (0.43) | TP53KDM4ECYP3A4MAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107964016-B | Thiophene derivatives | 天津合美医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-108059635-B | Thiophene derivatives | 天津合美医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-107722036-B | Thiophene derivatives | 天津合美医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |
| EP-2267046-A1 | Process for homo- or copolymerization of conjugated olefines | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1597292-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004076504-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-09-10 | — | — | WO | disclosed |