Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689158 | 0.98 | TP53 (0.42) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL821547 | 0.95 | TP53 (0.40) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL822038 | 0.95 | TP53 (0.40) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL10712270 | 0.81 | KDM4E (0.44) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| Hydrochloric Acid SCHEMBL27259194 | 0.79 | CYP3A4 (0.48) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL28136682 | 0.75 | TSHR (0.43) | TP53CALM1THRBNR1H2NR1H3 | |
| SCHEMBL16378246 | 0.74 | TP53 (0.48) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL1107767 | 0.74 | TP53 (0.48) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL843022 | 0.74 | CALM1 (0.45) | TP53KDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL231005 | 0.74 | ESR1 (0.56) | TP53KDM4ECYP3A4MAPTCALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160041-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | STYRON EUROPE GMBH | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160041-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | F12, ETFB, F2 | TP53 4774/4885KDM4E 3737/4885CYP3A4 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.