Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.54 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12280399 | 0.85 | P2RX7 (0.69) | P2RX7FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL10068409 | 0.85 | P2RX7 (0.74) | P2RX7FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL7101602 | 0.79 | FGFR1 (0.57) | P2RX7FGFR1FGFR2FGFR4FGFR3 | |
| Bilawsone SCHEMBL30884954 | 0.77 | APAF1 (0.75) | P2RX7ALDH1A1SMN1; SMN2MAPTNPC1 | |
| Bilawsone SCHEMBL3768549 | 0.77 | APAF1 (0.75) | P2RX7ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL27645881 | 0.75 | MAPT (0.86) | P2RX7FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL25390971 | 0.75 | TSHR (0.62) | TTRNPC1TP53RAB9AEGFR | |
| Anthraquinone SCHEMBL2542462 | 0.75 | TSHR (0.70) | ALDH1A1MAPTTTRNPC1TP53 | |
| SCHEMBL14773924 | 0.75 | ME2 (0.74) | FGFR1FGFR2FGFR4FGFR3ALDH1A1 | |
| SCHEMBL13770821 | 0.74 | FGFR1 (0.85) | P2RX7FGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241855-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2012-08-14 | — | — | US | claimed |
| EP-1325154-B1 | METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2007-08-01 | — | — | EP | claimed |
| US-7118868-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2006-10-10 | — | — | US | claimed |
| EP-1707642-A2 | Method for detecting cytosine methylations | Epigenomics AG (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-1294945-B1 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2006-08-30 | — | — | EP | claimed |
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | claimed |
| EP-1294945-A2 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | Epigenomics AG (DE) | 2003-03-26 | — | — | EP | claimed |
| WO-2001098528-A2 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2001-12-27 | — | — | WO | claimed |
| US-8377638-B2 | Process for the detection of cytosine methylations | QIAGEN GMBH (DE) | 2013-02-19 | — | — | US | disclosed |
| US-8241855-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20100297614-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2010-11-25 | — | — | US | disclosed |
| EP-1977011-B1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2010-07-28 | — | — | EP | disclosed |
| EP-1977011-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | Qiagen GmbH (DE) | 2008-10-08 | — | — | EP | disclosed |
| US-20070207472-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| EP-1325154-B1 | METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2007077262-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2007-07-12 | — | — | WO | disclosed |
| US-7118868-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2006-10-10 | — | — | US | disclosed |
| EP-1707642-A2 | Method for detecting cytosine methylations | Epigenomics AG (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1294945-B1 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | disclosed |