SCHEMBL4298080

SCHEMBL4298080

CCC(=O)Cn1ccnc1C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 2/20 0.51
ALPG P10696 2/20 0.51
ALPI P09923 1/20 0.51
PLAA Q9Y263 1/20 0.51
POLB P06746 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 2/20 0.50
GFER P55789 1/20 0.50
NOS1 P29475 1/20 0.49
FDPS P14324 1/20 0.46
KDM4E B2RXH2 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
RECQL P46063 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25401370 0.81 ALPL (0.51) ALPLALPGALPIPLAAPOLB
SCHEMBL12735399 0.81 ALPL (0.54) ALPLALPGALPIPLAAPOLB
SCHEMBL369240 0.81 ALPL (0.54) ALPLALPGALPIPLAAPOLB
SCHEMBL13623629 0.80 ALPG (0.35) ALPLALPGALPIPLAAPOLB
SCHEMBL1179644 0.79 ALPL (0.53) ALPLALPGALPIPLAAPOLB
Hydrochloric Acid SCHEMBL28835895 0.79 ALPL (0.55) ALPLALPGALPIPLAAPOLB
SCHEMBL28938190 0.79 ALPL (0.53) ALPLALPGALPIPLAAPOLB
SCHEMBL368204 0.79 POLB (0.51) ALPLALPGALPIPLAAPOLB
SCHEMBL23286087 0.78 ALPL (0.51) ALPLALPGALPIPLAAPOLB
Bicarbonate SCHEMBL28294813 0.77 ALDH1A1 (0.53) ALPLALPGALPIPLAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382946-A1 POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING Changzhou University (CN) 2023-11-30 US disclosed
US-20090176831-A1 Compounds and Methods for Treating Cancer and Diseases of the Central Nervous System OSTA BIOTECHNOLOGIES (CA) 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382946-A1 POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING PTMS, CBS, CHAMP1 ALPL 4493/4885ALPG 4546/4885ALPI 4851/4885
US-20090176831-A1 Compounds and Methods for Treating Cancer and Diseases of the Central Nervous System HMOX1, HMOX2, CYC1 ALPL 2646/4885ALPG 405/4885ALPI 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.