SCHEMBL3694249

SCHEMBL3694249

ClCCCCCCCCCCCCCCCCCCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 0.58
MAOA P21397 1/20 0.56
MAOB P27338 2/20 0.54
MAPT P10636 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879064 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL4306865 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL1006673 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL2582965 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL11254111 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL6680431 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL6678927 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL1271432 0.97 MAOA (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL11033070 0.95 MAOA (0.56) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL432616 0.90 SIGMAR1 (0.54) SIGMAR1MAOAMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709273-B2 Particles for diagnostic and therapeutic use SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2010-05-04 US disclosed
EP-1240522-B1 LIGHT-EMITTING PARTICLES FOR DIAGNOSTIC AND THERAPEUTIC USE SIEMENS HEALTHCARE DIAGNOSTICS (DE) 2009-10-28 EP disclosed
US-20060121506-A1 Particles for diagnostic and therapeutic use DADE BEHRING MARBURG GMBH 2006-06-08 US disclosed
US-7022529-B2 Particles for diagnostic and therapeutic use DADE BEHRING MARBURG GMBH (DE) 2006-04-04 US disclosed
US-20040241711-A1 Particles for diagnostic and therapeutic use SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2004-12-02 US disclosed
US-6703248-B1 POLYMERIC MATRIX HAVING DISSOLVED THEREIN, A PLASTICIZER A PHOTOSENSITIZER AND A CHEMILUMINESCENT COMPOUND; FOR USE AS BIO ASSAY DADE BEHRING MARBURG GMBH (DE) 2004-03-09 US disclosed
EP-1240522-A2 LIGHT-EMITTING PARTICLES FOR DIAGNOSTIC AND THERAPEUTIC USE Dade Behring Marburg GmbH (DE) 2002-09-18 EP disclosed
WO-2001044811-A2 PLASMINOGEN ACTIVATOR ASSAY INVOLVING AN ELASTASE INHIBITOR DADE BEHRING MARBURG BmbH (DE) 2001-06-21 WO disclosed
US-4052427-A PROCESS FOR THE PREPARATION OF DIALKYLTIN DIHALIDES WITCO CHEMICAL CORPORATION (US) 1977-10-04 US disclosed