SCHEMBL4306865

SCHEMBL4306865

ClCCCCCCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 0.58
MAOA P21397 1/20 0.56
MAOB P27338 2/20 0.54
MAPT P10636 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879064 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL1006673 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL2582965 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL3694249 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL11254111 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL6680431 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL6678927 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL1271432 0.97 MAOA (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL11033070 0.95 MAOA (0.56) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL432616 0.90 SIGMAR1 (0.54) SIGMAR1MAOAMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110408266-A Inorganic nano material prints ink and its preparation method and application TCL CORP 2019-11-05 CN claimed
CN-106975516-B The preparation method of magnetic rodlike high temperature resistant phase transfer catalyst 西北工业大学 2019-06-04 CN claimed
CN-106975516-A The preparation method of the bar-shaped high temperature resistant phase transfer catalyst of magnetic 西北工业大学 2017-07-25 CN claimed
CN-106398080-A Aminated cross-linked segmented copolymer/graphene composite material and preparation method thereof 北京化工大学 2017-02-15 CN claimed
US-4046819-A Alkylation of alkyl, cycloalkyl and aralkyl halides UOP INC. (US) 1977-09-06 US claimed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
US-11174337-B2 Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-16 US disclosed
EP-0645370-A1 Substituted m-xylylene diamines for the treatment of diseases of the central nervous system LILLY INDUSTRIES LIMITED (GB) 1995-03-29 EP disclosed
EP-0442115-B1 Process for nucleus-chlorination of aromatic hydrocarbons BAYER AG (DE) 1993-11-24 EP disclosed
US-5105036-A Friedel-Crafts catalyst and oxy-substituted cyclic amidines as cocatylsts; preferential formation of p-isomer BAYER AKTIENGESELLSCHAFT (DE) 1992-04-14 US disclosed
US-5061720-A ANTIINFLAMMATORY AGENTS FOR TOPICAL APPLICATION TO SKIN A. H. ROBINS COMPANY, INC. (US) 1991-10-29 US disclosed
EP-0442115-A1 Process for nucleus-chlorination of aromatic hydrocarbons BAYER AG (DE) 1991-08-21 EP disclosed
EP-0336361-B1 SULFUR-CONTAINING ACRYL OLIGOMER COMPOSITION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-04-10 EP disclosed
US-4990653-A Curable; plastic lenses; transparency, optical uniformity MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-02-05 US disclosed
EP-0336361-A1 Sulfur-containing acryl oligomer composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B SIGMAR1 4651/4885MAOA 2124/4885MAOB 2543/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B SIGMAR1 4625/4885MAOA 2042/4885MAOB 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.