SCHEMBL1006673

SCHEMBL1006673

ClCCCCCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 0.58
MAOA P21397 1/20 0.56
MAOB P27338 2/20 0.54
MAPT P10636 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879064 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL4306865 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL2582965 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL3694249 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL11254111 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL6680431 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL6678927 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL1271432 0.97 MAOA (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL11033070 0.95 MAOA (0.56) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL432616 0.90 SIGMAR1 (0.54) SIGMAR1MAOAMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117779469-A Construction method of host and guest of photodynamic/quaternary ammonium salt/boric acid antibacterial composite PET fiber coating 浙江豪欣纺织有限公司 2024-03-29 CN claimed
CN-109422858-A A kind of polyalcohol being grafted UV absorption agent molecule 中国铁道科学研究院铁道建筑研究所 2019-03-05 CN claimed
CN-106398080-B A kind of ammonium cross-linking type block copolymer/graphene composite material and preparation method thereof 北京化工大学 2018-12-04 CN claimed
CN-106398080-A Aminated cross-linked segmented copolymer/graphene composite material and preparation method thereof 北京化工大学 2017-02-15 CN claimed
CN-103709110-B A kind of preparation method of erlotinid hydrochloride key intermediate APELOA KANGYU PHARMACEUTICAL CO., LTD. (CN) 2016-05-04 CN claimed
US-20100223716-A1 PROTECTIVE ARTICLES CONTAINING N-HALOCHITOSAN E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-09 US claimed
US-20080289088-A1 N-ALKYLCHITOSAN FILMS AND LAMINATES MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-11-27 US claimed
US-7199043-B2 Method of forming copper wiring in semiconductor device HYNIX SEMICONDUCTOR INC. (KR) 2007-04-03 US claimed
US-20050009339-A1 Method of forming copper wiring in semiconductor device KEY FOUNDRY CO., LTD. (KR) 2005-01-13 US claimed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
CN-117779469-A Construction method of host and guest of photodynamic/quaternary ammonium salt/boric acid antibacterial composite PET fiber coating 浙江豪欣纺织有限公司 2024-03-29 CN disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
CN-112110864-B 4-amide substituted pyrimidine targeted DDR1 inhibitor, preparation method thereof and application of inhibitor in antitumor activity 温州医科大学 2022-07-22 CN disclosed
US-3933897-A ANTIULCER, ASTHMA, RENAL DYSFUNCTION THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933898-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933896-A ANTICOAGULANTS, ASTHMA, LABOR INDUCERS, CERVICAL DILATION THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933895-A PROSTAGLANDINS, ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933899-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3931289-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B SIGMAR1 4651/4885MAOA 2124/4885MAOB 2543/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B SIGMAR1 4625/4885MAOA 2042/4885MAOB 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.